| dc.contributor.author | Olewe, Tom M. | |
| dc.contributor.author | Mwanthi, Mutuku A | |
| dc.contributor.author | Wang'ombe, Joseph K. | |
| dc.contributor.author | Griffiths, Jeffrey K. | |
| dc.date.accessioned | 2013-02-26T08:32:41Z | |
| dc.date.issued | 2008 | |
| dc.identifier.citation | Journal of Applied Biosciences (2008), Vol. 10: 483 - 487." | en |
| dc.identifier.uri | : www.biosciences.elewa.org | |
| dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/11562 | |
| dc.description.abstract | Objective: To evaluate LeadCare II analyzer, a portable electro-analytical instrument used to rapidly
analyze blood lead levels (BLL) in children, and compare it to gold standard, graphite furnace atomic absorption spectrometry (GFAAS)
Methodology and results: Twenty two (22) duplicate fresh capillary blood samples were tested using both LeadCare II kits and GFAAS. There was a strong, positive correlation (r = 0.787, r2 = 0.62) between the BLL determined by LeadCare II and GFAAS. In this study, LeadCare II analyzer scored 57% sensitivity, 80% specificity and positive predictive value (PPV) of 0.8. However, its predictive value depends on prevalence of disease and the number of individuals.
Conclusion and application of findings: LeadCare II offers an opportunity to cost effectively screen for childhood lead poisoning in Kenya. Deployment and use of this technology could improve patient care by providing instant results. During a visit to a health centre, lead levels can be determined and treatment initiated immediately where necessary | en |
| dc.language.iso | en | en |
| dc.subject | Blood lead levels, | en |
| dc.subject | Kenya, | en |
| dc.subject | GFAAS, | en |
| dc.subject | LeadCare II analyzer | en |
| dc.title | Evaluation of a portable blood lead analyzer as an alternative to graphite furnace atomic absorption spectrophotometer | en |
| dc.type | Article | en |
| local.publisher | Department of Community Health, School of Medicine, University of Nairobi, Kenya; | en |
| local.publisher | Department of Public Health and Family Medicine, Tufts University, Boston, MA, USA | en |
