Cc868t Single nucleotide polymorphism and HIV Type 1 Disease progression among postpartum women in Kenya

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Date
2012
Author
Choi Robert Y.
Fowke Keith R.
Juno Jennifer
Lohman-Payne Barbara
Oyugi Julius O.
Brown Elizabeth R.
Bosire Rose.
John-Stewart Grace.
Farquhar Carey.
Type
Article
Language
en
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Abstract
The C868T single nucleotide polymorphism in the CD4 receptor encodes an amino acid substitution of tryptophan for arginine in the third domain. Previous studies suggest that C868T increases the risk of HIV-1 acquisition; however, the influence of this single nucleotide polymorphism (SNP) on disease progression has not been established. The presence of the C868T polymorphism was not statistically significantly associated with HIV-1 disease progression outcomes in a cohort of postpartum Kenyan women
URI
http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/12200
http://online.liebertpub.com/doi/pdf/10.1089/aid.2011.0095
Citation
AIDS RESEARCH AND HUMAN RETROVIRUSES Volume 28, Number 6, 2012
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