| dc.contributor.author | Jaoko Walter G. | |
| dc.contributor.author | Muchemi, G | |
| dc.contributor.author | Oguya, FO | |
| dc.date.accessioned | 2013-04-04T07:37:38Z | |
| dc.date.available | 2013-04-04T07:37:38Z | |
| dc.date.issued | 1996 | |
| dc.identifier.citation | East Afr Med J. 1996 Aug;73(8):499-501 | en |
| dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/8898462 | |
| dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/15265 | |
| dc.description.abstract | Four hundred and thirty six pupils in two primary schools in Kibwezi, Kenya aged between seven and sixteen years and positive for S. mansoni were treated as follows: 320 pupils with a single dose of praziquantel at 40 mg/kg body weight and 116 controls with a placebo. Immediate and delayed side effects of praziquantel were observed. The main side-effects were abdominal pain (36.3%), headache (35.3%) and nausea (13.1%). There was correlation between frequencies of these side-effects and intensity of infection measured as eggs per gram of faeces. Other side-effects included dizziness (9.7%), fever (7.8%), urticaria and bloody diarrhoea. Overall, the side-effects of praziquantel were mild and transient, and did not require any intervention. For ethical reasons, all pupils who served as controls were treated with praziquantel after the study | en |
| dc.language.iso | en | en |
| dc.title | Praziquantel side-effects during treatment of Schistosoma mansoni infected pupils in Kibwezi, Kenya | en |
| dc.type | Article | en |
| local.publisher | Department of Medical Microbiology, College of Health Sciences, University of Nairobi | en |
