dc.contributor.author | Kristen, Sweet | |
dc.contributor.author | Bosire, Claire | |
dc.contributor.author | Busola, Sanusi | |
dc.contributor.author | Carly, Sherrod | |
dc.contributor.author | Kwatampora, Jessie | |
dc.contributor.author | Wairimu, Waweru | |
dc.contributor.author | Mugo, Nelly | |
dc.contributor.author | Kimani, Joshua | |
dc.contributor.author | Jie, Ting | |
dc.contributor.author | Jennifer, Clark | |
dc.contributor.author | Dirk, Dittmer | |
dc.contributor.author | Jennifer, Smith | |
dc.date.accessioned | 2020-06-05T11:03:40Z | |
dc.date.available | 2020-06-05T11:03:40Z | |
dc.date.issued | 2020 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke/handle/11295/152793 | |
dc.description.abstract | Female sex workers (FSWs) have a notably high risk of acquiring human papillomavirus (HPV) infections. Relatively few studies address the type-specific prevalence and incidence of HPV among FSWs in sub-Saharan Africa. FSWs (n = 348) attending the Korogocho clinic in Nairobi, Kenya participated from August 2009 to March 2011. HPV DNA was detected using the SPF10-LiPA25 PCR assay. Baseline prevalence of HPV infection and cervical dysplasia were calculated, stratified by HIV-serostatus. Incidence rate (IR) of infection was calculated as number of new infections from baseline over person-months among 160 HPV-negative participants with complete 12-month follow-up. Baseline HPV prevalence was 23.6% for any HPV and 20.4% for high-risk HPV (hrHPV) types. Most prevalent types were HPV52 (10.1%), HPV35 (2.3%), and HPV51 (2.3%). A quarter (24%) of participants were HIV-positive. HPV prevalence was higher in HIV-positive (32.1%) than HIV-negative (20.8%) participants. hrHPV prevalence was higher in HIV-positive (27.4%) than HIV-negative (18.2%) women. During follow-up, HPV IR was 31.4 (95% CI: 23.8–41.5) for any HPV and 24.2 (95% CI: 17.9–32.8) for hrHPV types. HPV52 had the highest IR (6.0; 95% CI: 6.5–10.3). Overall HPV and hrHPV prevalence were lower than expected, but both prevalence and incidence were higher in HIV-positive than in HIV-negative women. | en_US |
dc.language.iso | en | en_US |
dc.publisher | UoN | en_US |
dc.rights | Attribution-NonCommercial-NoDerivs 3.0 United States | * |
dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/us/ | * |
dc.subject | Human Papillomavirus Types in Female Sex Workers | en_US |
dc.title | Prevalence, Incidence, and Distribution of Human Papillomavirus Types in Female Sex Workers in Kenya | en_US |
dc.type | Thesis | en_US |