Prevalence and antimicrobial susceptibility of bacteria implicated in neonatal sepsis at Pumwani Maternity Hospita
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Date
2020-09-03Author
Maore, N. K.
Karimi, P. N.
Guantai, E. M.
Type
ArticleLanguage
en_USMetadata
Show full item recordAbstract
Neonatal sepsis is one of the most common causes of morbidity and mortality among
infants in developing countries. The etiology and antimicrobial sensitivity patterns of
bacteria responsible vary in different hospitals. This study identified bacteria in blood
cultures of neonates with clinically suspected septicemia and demonstrated their
susceptibility patterns. A longitudinal design targeting all neonates at Pumwani
maternity hospital with suspected sepsis was used. One hundred and fifty neonates
were selected using consecutive sampling. Data was collected using a questionnaire.
Out of 150 blood specimens cultured, the cases of confirmed bacterial sepsis were
48(32%). Gram-positive pathogens predominated with Staphylococcus aureus and
Streptococcus viridans accounting for 70%. The only Gram-negative isolates were E.
coli and Klebsiella spp. Gram-positive isolates showed high sensitivity (above 80%) to
meropenem, gentamicin, ceftriaxone, ofloxacin, and amikacin. Gram- negative
organisms were generally resistant to penicillins and absolutely sensitive to
meropenem, ceftazidime and ciprofloxacin
URI
http://uonjournals.uonbi.ac.ke/ojs/index.php/ecajps/article/view/583http://erepository.uonbi.ac.ke/handle/11295/153588
Citation
Maore, N. K., Karimi, P. N., & Guantai, E. M. (2020). Prevalence and Antimicrobial Susceptibility of Bacteria Implicated in Neonatal Sepsis at Pumwani Maternity Hospital. East and Central African Journal of Pharmaceutical Sciences, 23(2), 67-71.Publisher
East Cent. Afr. J. Pharm. Sci
Collections
- Faculty of Health Sciences (FHS) [10378]