The effect of depo-provera on the platelet function, plasma fibrinogen concentration and haemoglobin level in women attending the family planning clinic at Kenyatta national hospital, Nairobi.

Abstract

The effect of "Depo-Provera" on the platelet function, plasma fibrinogen concentration and Hamoglobin level in 75 women attending the family planning clinic at Kenyatta National Hospital was studied. A similar number of women not using any contraceptives, but attending the Female filter clinic at Kenyatta National Hospital, were matched for age with the study group and similarly studied as above. The results obtained showed significant differe- nces between the control and the study group that could predispose to a "hyper coagulable state" in women on Depo-Provera, in the following variables:- Haemoglobin concentration, platelet Count, platelet aggregabi ty, clot Retraction, and fibrinogen concentration. The variable platelet adhesive- did not show any statistically significant differences between the study and the control group