Pharmacological activities of Lantana trifolia on isolated guinea pig trachea and rat phrenic nerve diaphragm

Abstract

A methanol extract of L. trifolia produced bronchodilation of isolated guinea pig trachea comparable to that of salbutamol. The plant extract reduced bronchoconstriction induced by histamine, 5-HT and acetylcholine on isolated guinea pig trachea. Physostigmine failed to inhibit neuromuscular blocking activity of the extract on rat phrenic nerve diaphragm