| dc.contributor.author | John-Stewart, GC | |
| dc.contributor.author | Nduati, RW | |
| dc.contributor.author | Rousseau, CM | |
| dc.contributor.author | Mbori-Ngacha, DA | |
| dc.contributor.author | Richardson, BA | |
| dc.contributor.author | Rainwater, S | |
| dc.contributor.author | Panteleeff, DD | |
| dc.contributor.author | Overbaugh, J | |
| dc.date.accessioned | 2013-04-29T08:54:36Z | |
| dc.date.available | 2013-04-29T08:54:36Z | |
| dc.date.issued | 2005-08-01 | |
| dc.identifier.citation | Journal of Infectious Diseases. 2005;192(3):492-6 | en |
| dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/15995964 | |
| dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/17529 | |
| dc.description | Journal article | en |
| dc.description.abstract | The prevalence of human immunodeficiency virus (HIV)-1-infected cells and HIV-1 RNA levels in genital secretions and breast milk and the risk of mother-to-child transmission of HIV-1 were compared among subtypes A, C, and D in a Kenyan cohort. Pregnant women infected with subtype C were significantly more likely to shed HIV-1-infected vaginal cells than were those infected with subtype A or D (odds ratio [OR], 3.6 [95% confidence interval {CI}, 1.4-8.8]; P = .006). This relationship held after adjusting for age, CD4 cell count, and plasma HIV-1 RNA load (OR, 3.1 [95% CI, 1.1-8.6]; P = .03). These observations suggest that HIV-1 subtype influences mucosal shedding of HIV-1. | en |
| dc.language.iso | en | en |
| dc.subject | Subtype C | en |
| dc.subject | Vaginal shedding of HIV-1 vaginal shedding of HIV-1. | en |
| dc.title | Subtype C Is associated with increased vaginal shedding of HIV-1. | en |
| dc.type | Article | en |
| local.publisher | Department of paediatrics, University of Nairobi | en |
