| dc.contributor.author | Guantai, A.N | |
| dc.date.accessioned | 2013-04-29T12:44:59Z | |
| dc.date.available | 2013-04-29T12:44:59Z | |
| dc.date.issued | 1989 | |
| dc.identifier.citation | East and Central African journal of pharmaceutical sciences - vol.1 1989 | en |
| dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/17763 | |
| dc.description.abstract | Cardiovascular activities of nitidine chloride from Zanthoxylunt chalybeum have been compared with those of 9-methoxychelerythrine. Whereas nitidinc chloride was found to show significant hypotensive activity in rabbits, 9-methoxychelerythrine chloride showed no hypotensive activity. The effect of nitidine chloride on isolated rabbit heart was also compared with those of adrenaline and acetylcholine. 9-Methoxychelerythrine, which has hitherto been regarded as an artefact formed by recrystallization of chelerythrine base from methanol, has been shown in this work to be a true natural constituent of Zanthoxylum chalybeum. Keywords: 9-inethoxychelerythrine; nitidine chloride; cardiovascular properties; hypotensive effect; Zanthoxylum chalybeum. | en |
| dc.language.iso | en | en |
| dc.title | Comparative Examination of Two Zanthoxylum Benzophenanthridine Alkaloids for Cardiovascular Effects in Rabbits | en |
| dc.type | Article | en |
