dc.contributor.author | Karuru, J W | |
dc.date.accessioned | 2013-05-23T09:19:39Z | |
dc.date.available | 2013-05-23T09:19:39Z | |
dc.date.issued | 2004 | |
dc.identifier.citation | Master of Medicine (internal Medicine) in the Faculty of Medicine, University of Nairobi 2004 | en |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/24758 | |
dc.description.abstract | Objective: To determine the seroprevalence and genotypes of HCV infection
and prevalence of HIV co-infection among various broad subgroups of the
Kenyan population.
Study Design and Setting: This was a prospective cross-sectional descriptive
study, done at KNH, a tertiary referral and teaching hospital, inpatient and
outpatient departments and the National Blood Transfusion Services Center,
Nairobi.
Subjects:
1. Volunteer blood donors
2. Hospital staff, KNH
3. HIV/AIDS and HIV negative in-patients at KNHmedical wards
4. VCTAttendants
Methods: After recruitment, the above subjects were assessed for risk factors
for HCV/HIV transmission through a questionnaire. Blood for determination of
HCVseropositivitiy and genotypes was obtained.
Results: The prevalence of HCV/HIV co-infection among 6154 blood donors in
the NBTSCwas very low, at <0.02%. The prevalence of HCV infection among
977 KNH staff was 3.6%. Among 458 HIV/AIDS medical in-patients, the
prevalence of HCV was 3.7% while in the 518 HIV negative patients, it was
4.4%. The prevalence of co-infection with HCV and HIV was 3.7%. The HIV
prevalence among the 353 KNH HIV-VCT attendees was 9.3%, none of the
clients tested positive for HCV.The genotypes for 5 patients was done; all were
genotype 4. The incidence of risk factors in the persons with HCV and/or HIV
infection(s) was low. | en |
dc.language.iso | en | en |
dc.publisher | University of Nairobi | en |
dc.title | Prevalence of HCV, genotypic subtypes and HCV-HIV co-infection in various broad subgroups of the Kenyan population | en |
dc.type | Thesis | en |
dc.description.department | a
Department of Psychiatry, University of Nairobi, ; bDepartment of Mental Health, School of Medicine,
Moi University, Eldoret, Kenya | |
local.publisher | School of Medicine | en |