Correlation of signs, symptoms and histology to the weight of prostate in Benign Prostatic Hyperplasia

Abstract

29 patients with clinical diagnosis of Benign Prostatic enlargement were studied. Post-voiding residual urine volume was measured for all the patients who did not have catheter in-situ and for those who were catheterised were taken to have at least 200mls according to the criteria used by Hiroshi Ohe, M.D.19 The patients then underwent open prostatectomies using retropubic and transversical routes. The wet weights of the enucleated adenomas was taken after which the prostatic specimens were prepared for histology. Staining was done with haematoxylin and eosin. A median of 6 blocks were prepared per prostate by routine section technique. Residual urine volume, compared to the weights of the prostates was found to have a significant relationship (t2 27=3.16 P>O. 001). Mean weights of prostates varied with histological type but the relationship was not statistically significant (F2,27=1.393, P>0.05). Prostates with predominantly stromal type were not necessarily smaller than those of other histological types. Thus failing to prove the dogma that smaller

prostates are fibrotic (Blandy, Dorflinger)