dc.contributor.author | Ndege, K | |
dc.date.accessioned | 2013-05-23T12:23:51Z | |
dc.date.available | 2013-05-23T12:23:51Z | |
dc.date.issued | 2008 | |
dc.identifier.citation | Master of Medicine in Internal Medicine | en |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/11295/24896 | |
dc.description.abstract | Objectives: To evaluate the empirical diagnoses of PCP made at Kenyatta National
Hospital.
Design: A case series of 54 patients, seen at the Kenyatta Hospital over 12 weeks.
Setting: General medical wards of Kenyatta National Hospital, a tertiary care,
university teaching hospital in Nairobi, Kenya.
Cases: Patients with an authoritative presumptive diagnosis of PCP made within the
medical wards at KNH and definitive treatment started.
Methods: Patients diagnosed with PCP were identified and their clinical parameters
recorded .. Suitable patients underwent nebulization with hypertonic 4% saline and
sputa induced. The sputa were subjected to bacterial and fungal cultures, ZN staining
and IFAT staining for Pjiroveci.
Results: 54 patients were diagnosed with PCP empirically during this period. Sputum
induction was performed on 40 of the patients who fulfilled the inclusion criteria. P. j
cysts were isolated in 27 of the specimens, 4 had equivocal results and 9 had negative
results. Other organisms isolated were Klebsiella pneumoniae (8 patients) E. coli,
Streptococci pneumoniae, Aspergillus sp. in 4 patients. 14 patients had P. jiroveci
cysts isolated together with these other organisms in a mixed infection. The patient's
ages ranged from19-61 yrs and 37.5% were male while 62.5% were female. Cough
and dyspnoea were the ubiquitous presenting features in these patients. All the
patients were HIV +ve but only 23 (58%) were diagnosed prior to the diagnosis of
PCP. Only 8 (20%) of the patients were on HAART. Only 6 (15%) of the patients
were on PCP prophylaxis. 34 (85%) of the patients presented in advanced HIV
disease, stage III/IV. For the remainder, PCP was the AIDS defining illness | en |
dc.description.sponsorship | University of Nairobi | en |
dc.language.iso | en | en |
dc.title | An evaluation of the empirical diagnosis of pneumocystis pneumonia at Kenyatta national hospital | en |
dc.type | Thesis | en |
dc.description.department | a
Department of Psychiatry, University of Nairobi, ; bDepartment of Mental Health, School of Medicine,
Moi University, Eldoret, Kenya | |