Association Between Cervical Shedding Of Herpes Simplex Virus And Hiv-1.aids

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Date
2002-12-06
Author
Mcclelland, R S
Wang, C C
Overbaugh, J
Richardson, B A
Corey, L,
Ashley, R L
Mandaliya, K
Ndinya-Achola, JO
Bwayo, JJ
Kreiss, J K
Type
Article
Language
en
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Abstract
OBJECTIVE: To investigate the association between the cervical shedding of herpes simplex virus (HSV) and HIV-1. DESIGN: A cross-sectional study on 200 women seropositive for both HSV-2 and HIV-1 was conducted in a family planning clinic at the Coast Provincial General Hospital, Mombasa, Kenya. MAIN OUTCOME MEASURES: Quantities of HSV DNA (types 1 and 2) and HIV-1 RNA as well as the presence or absence of HIV-1 proviral DNA in cervical secretions were determined and compared. RESULTS: There was a significant correlation between the quantities of HSV DNA and HIV-1 RNA in the cervical secretions of HSV-shedding women (Pearson's r = 0.24
URI
http://www.ncbi.nlm.nih.gov/pubmed/12461416
http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/27579
Citation
Mcclelland Rs, Wang Cc, Overbaugh J, Richardson Ba, Corey L, Ashley Rl, Mandaliya K, Ndinya-achola J, Bwayo Jj, Kreiss Jk.association Between Cervical Shedding Of Herpes Simplex Virus And Hiv-1.aids. 2002 Dec 6;16(18):2425-30., O., Prof. Ndinya-achola J. , Aids. 2002 Dec 6;16(18):2425-30., (2002)
Publisher
University of Nairobi
 
School of Medicine
 
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