Identification And Estimation Of A Cholinomimetic Substance In The Venom Of Dendroaspis Polylepis Res. Commun. Chem. Pathol. Pharmacol.

Thumbnail
View/Open
Date
1982
Author
Mbugua, P M
Thairu, K
Telang, B V
Type
Article
Language
en
Metadata
Show full item record

Abstract
A cholinomimetic substance was isolated from desiccated venom of Dendroaspis polylepis by one-dimensional ascending paper chromatography. The migratory and staining properties of the substance were compared with those of standard acetylcholine. Pharmacological and biochemical identification was carried out on various in vitro and in vivo biological test objects as well as with high-voltage paper electrophoresis. The assay of the cholinomimetic substance was done on both superfused guinea pig ileum and hamster stomach strips. The cholinomimetic substance content was 2.44 - 3.46mg/0.96gm of total protein in the desiccated venom.
URI
http://profiles.uonbi.ac.ke/pmungai/publications/mbugua-p-m-thairu-k-and-telang-b-v-1982-identification-and-estimation-cholinomi
http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/28307
http://www.ncbi.nlm.nih.gov/pubmed/7100627
Citation
Mbugua P M Thairu K And Telang B V (1982): Identification And Estimation Of A Cholinomimetic Substance In The Venom Of Dendroaspis Polylepis Res. Commun. Chem. Pathol. Pharmacol. 36: 187-, Mungai, Dr. Mbugua Paul , Federation Of Analytical Chemistry And Spectroscopy Society (facss) Xv, Boston, November 1988, (1982)
Publisher
Department of biochemistry, university of Nairobi
Collections