Cell-free human immunodeficiency virus type 1 in breast milk

dc.contributor.author	Lewis, P
dc.contributor.author	Nduati, RW
dc.contributor.author	Kreiss, JK
dc.contributor.author	John, GC
dc.contributor.author	Richardson, BA
dc.contributor.author	Mbori-Ngacha, DA
dc.contributor.author	Ndinya-Achola, JO
dc.contributor.author	Overbaugh, J
dc.date.accessioned	2013-05-31T12:05:34Z
dc.date.available	2013-05-31T12:05:34Z
dc.date.issued	1998
dc.identifier.citation	J Infect Dis. 1998 Jan;177(1):34-9	en
dc.identifier.uri	http://www.ncbi.nlm.nih.gov/pubmed/9419167
dc.identifier.uri	http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/28344
dc.description.abstract	Breast-feeding may be an important route of human immunodeficiency virus type 1 (HIV-1) vertical transmission in settings where it is routinely practiced. To define the prevalence and quantity of HIV-1 in cell-free breast milk, samples from HIV-1-seropositive women were analyzed by quantitative competitive reverse transcription-polymerase chain reaction (QC-RT-PCR). HIV-1 RNA was detected in 29 (39%) of 75 specimens tested. Of these 29 specimens, 16 (55%) had levels that were near the detection limit of the assay (240 copies/mL), while 6 (21%) had >900 copies/mL. The maximum concentration of HIV-1 RNA detected was 8100 copies/mL. The prevalence of cell-free HIV-1 was higher in mature milk (47%) than in colostrum (27%	en
dc.language.iso	en	en
dc.publisher	University of Nairobi	en
dc.title	Cell-free human immunodeficiency virus type 1 in breast milk	en
dc.type	Article	en
local.publisher	Faculty of medicine	en