Excretion of the active principle of of Catha edulis (Miraa) in human urine.

Abstract

d-Norpseudoephedrine, a central stimulant present in Catha edulis, is excreted unchanged in human urine. The alkaloid was detected in urine 30-50 min after ingestion of synthetic d-norpseudoephedrine, and trace amounts of the drug could still be detected 24 hr later. Approximately 40% of ingested d-norpseudoephedrine was recovered in urine in the first 6 hr.