dc.contributor.author | Masesa, Jan V | |
dc.date.accessioned | 2013-06-07T06:18:13Z | |
dc.date.available | 2013-06-07T06:18:13Z | |
dc.date.issued | 2003 | |
dc.identifier.citation | Masesa, I. V(2003).Deep venous thrombosis of the lower limb: evaluation of duplex ultrasound imaging versus venography prospective blinded comparative study done at the Kenyatta National Hospital (Nairobi) | en |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/11295/29663 | |
dc.description | Master of Medicine thesis | en |
dc.description.abstract | Introduction: Colour duplex ultrasound examination was carried
out on 55 limbs of patients referred to the Radiology department of the
Kenyatta National Hospital for contrast venography. The indication for
the contrast study was clinical suspicion of deep venous thrombosis of
the lower limb/s.
Objectives: To compare the findings of duplex ultrasound and
contrast venography in the detection of DVT of the lower limb and in
the process, establish the ability of colour duplex sonography
compared to venography, the gold standard.
Design: Prospective blinded comparative study
Subject: 44 patients (55 limbs) were seen during the study
period.
Setting: The departments of diagnostic radiology at KNH and
University of Nairobi.
Methods: An extra colour duplex ultrasound examination was given to
patients, free of charge. This was done within 24 hours of a successful
venography examination.
Main outcome measure: Sensitivity, specificity, predictive
values and accuracy of colour duplex ultrasound in detection of DVT
of the lower limbs, as it is done locally.
Results: A total of 55 limbs in 44 patients were examined. 30 males
and 14 females were seen. Most patients seen (66%) were between
26 and 45 years. A comparable number of left (25) and right (30) limbs
were studied. 19 limbs were positive for DVT by venography and 18 by
ultrasound. There were 2 false positives and 3 false negatives. In 63%
of the positive limbs, thrombosis was in the popliteal vein, only 3 cases
of isolated calf DVT were seen. The overall sensitivity was 88.9%,
specificity 91.8%, positive and negative predictive value 84% and
94.3% respectively. Accuracy was 90.9%. Considering only DVT
above the calf, the validity properties improve to 100%. An alternative
diagnosis was suggested by duplex ultrasound in 48% of the negative
cases.
Conclusion: The sensitivity specificity and accuracy of colour
duplex sonography in the detection of DVT of-the lower limbs is high.
These findings compare favourably to those done in western countries.
We feel that all patients with clinical suspicion of DVT should have
ultrasound done as the first investigation and venography be reserved
for those with equivocal or inadequate sonography results | en |
dc.language.iso | en | en |
dc.subject | Venous Thrombosis | en |
dc.subject | Lower limb | en |
dc.subject | Duplex Ultrasound imaging | en |
dc.subject | Venography | en |
dc.subject | Kenyatta National Hospital | en |
dc.title | Deep venous thrombosis of the lower limb: evaluation of duplex ultrasound imaging versus venography prospective blinded comparative study done at the Kenyatta National Hospital (Nairobi) | en |
dc.type | Thesis | en |
dc.description.department | a
Department of Psychiatry, University of Nairobi, ; bDepartment of Mental Health, School of Medicine,
Moi University, Eldoret, Kenya | |
local.publisher | Department of Diagnostic Radilogy, University of Nairobi | en |