Myocardial depressant fraction in the venom of Dendroaspis angusticeps

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Date
1980
Author
K, Thairu
BV, Telang
S, Mungai
N, Ng'ang'a J
J, Wangai
Type
Article
Language
en
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Abstract
Whole venom Dendroaspis angusticeps produced a negative chronotropic and ionotropic effect on the heart. Isolation of the fraction (T39) produced the same effect. Negative inotropic effect was blocked by atropine. The bradycardia may be due to a cholinergic effect and the negative ionotropic to a direct depressant effect on the myocardium.
URI
http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/30538
http://www.ncbi.nlm.nih.gov/pubmed/7364462
Citation
Indian J Physiol Pharmacol. 1980 Jan-Mar;24(1):61-4.
Publisher
Indian J Physiol Pharmacol
 
Department of Medicine, University of Nairobi
 
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