The Board of Adult Education Mandates and Goals

Abstract

Tetralones were converted to tetralinylamines via Leuckart reaction.These were then used to protect carboxamide side-chains of glutamine and asparagine. Clevage studies using trifluoroacetic acid and boron tristrifluoroacetate were then done on these derivatives. The groups 1-tetralinyl, 5,7-dimethyl-1-tetralinyl and 7-methoxy-1-tetralinyl were found to be good carboxamide protecting groups in asparagine.