The comparative antigenic characterization of Newcastle disease virus strains isolated in Kenya and Kazakhstan

Abstract

Twenty six Newcastle disease viruses — 12 reference strains and 14 strains isolated in Kenya and Kazakhstan — were characterized by means of a large panel of 38 monoclonal antibodies (MAB) directed against all the three envelope proteins: matrix, hemagglutinin-neuraminidase and fusion. The essential distinctions were revealed between the viruses isolated in Kenya and Kazakhstan while the differences amongst the viruses belonging to the same local group were much smaller. The heterogeneity amongst the viruses isolated in Kenya was more expressed as compared to the Kazakhstanian strains.