Rotenoids, isoflavones and chalcones from the stem bark of Millettia usaramensis subspecies usaramensis
Date
1998-01Author
Yenesew, Abiy
Midiwo, Jacob O
Waterman, Peter G
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
From the stem bark of Millettia usaramensis subsp. usaramensis four new 12a-hydroxyrotenoids with the unusual trans B/C ring junction ((+)-12a-epimillettosin, (+)-usararotenoid-A, (+)-12-dihydrousararotenoid-A, and (+)-usararotenoid-B), a new α-hydroxydihydrochalcone (α,4,2′-trihydroxy-4′-O-geranyldihydrochalcone), a new isoflavone, (norisojamicin), and a new cinnamyl alcohol derivative (4-O-geranylcinnamyl acetate) have been isolated and characterized. In addition, the known compounds 4′-O-geranylisoliquiritigenin, isoliquiritigenin, barbigerone, jamaicin and maximaisoflavone-G were identified. The structures were determined on the basis of spectroscopic evidence and chemical transformations.
New rotenones, isoflavones and dihydrochalcones have been obtained from the stem bark of Millettia usaramensis (Leguminosae) and identified by spectroscopic analysis. Novel 12a-hydroxyrotenoids are shown to have 6aR,12aS (6a-β, 12a-α) stereochemistry
URI
http://www.sciencedirect.com/science/article/pii/S003194229700424Xhttp://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/34891
Citation
Phytochemistry Volume 47, Issue 2, January 1998, Pages 295–300Publisher
University of Nairobi Department of Chemistry, University of Nairobi