Chinchona Alkaloid from Dendrosenecio kilimanjari subsp. cottonii

Abstract

Investigation of the Tanzanian Dendrosenecio kilimanjari subsp. cottonii resulted in the isolation of the cinchona alkaloid, cinchonidine (2). Conversion of cinchonidine to deoxy-cinchonidine was achieved in high yield using zinc dust in aqueous sulphuric acid. This illustrates the first reduction of a quinoline system using these reagents.