Outcome of intervention with or without low dose oral interferon alpha in thirty-two HIV-1 seropositive patients in a referral hospital
![Thumbnail](/bitstream/handle/11295/37330/ABSTRACT.%20pdf.jpg?sequence=9&isAllowed=y)
View/ Open
Date
1990-07Author
Obel, AO
Koech, DK
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Thirty two critically ill patients were admitted to Kenyatta National Hospital with a diagnosis of HIV-1 seropositivity on both ELISA and Western Blot between October 1989 and January 1990. Sixteen of the patients received low dose oral interferon alpha while the other 16 patients received intensive supportive management alone. Of the 16 patients who received low dose interferon alpha, 14 were discharged from the Hospital within 2 to 4 weeks of admission in a reasonable state of health while two of the patients died after 18 and 42 days from the time of admission. All the 16 patients who received intensive supportive management alone were dead within 4 weeks of entering the Hospital, their mean (+/- SD) stay after admission being 8.6 +/- 6.8 days. These results suggest that low dose oral interferon alpha may be of value in the care of critically ill HIV-1 seropositive patients.
URI
http://www.ncbi.nlm.nih.gov/pubmed/1977577http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/37330
Citation
East Afr Med J. 1990 Jul;67(7 Suppl 2):SS71-6.Publisher
University of Nairobi Department of Medicine, University of Nairobi
Collections
- Faculty of Health Sciences (FHS) [10378]