| dc.contributor.author | Kakai, R | |
| dc.contributor.author | Wamola, IA | |
| dc.contributor.author | Bwayo, JJ | |
| dc.date.accessioned | 2013-06-25T14:31:19Z | |
| dc.date.available | 2013-06-25T14:31:19Z | |
| dc.date.issued | 1995-04 | |
| dc.identifier.citation | East Afr Med J. 1995 Apr;72(4):217-9. | en |
| dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/7621754 | |
| dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/39879 | |
| dc.description.abstract | The purpose of this study was to determine the role of intestinal specific rotavirus IgA antibody in protection against diarrhoea due to rotavirus infection. Stool from children aged below 5 years with diarrhoea who reported to the Paediatric Observation Ward, Kenyatta National Hospital were examined for micro-organisms and IgA antibody. Specific rotavirus IgA antibody and antigen were determined using enzyme linked immunosorbent assay technique. Out of 153 stool specimens, 22% (34/153) were positive for rotavirus antigen and 15% (23/153) had IgA specific antibody to rotavirus. Children with specific IgA to rotavirus had no rotavirus except in two cases (p < 0.05). There was no difference in levels of specific IgA antibody between normal and malnourished children (p = 0.4). It is probable that intestinal specific IgA to rotavirus protects children against rotavirus diarrhoea. | en |
| dc.language.iso | en | en |
| dc.publisher | University of Nairobi | en |
| dc.title | Association of human rotavirus infection and intestinal rotavirus-specific immunoglobulin A in children with diarrhoea | en |
| dc.type | Article | en |
| local.publisher | College of Health Sciences,University of Nairobi | en |
