Busseihydroquinones A-D From The Roots Of Pentas Bussei
Date
2012-07Author
Yenesew, Abiy
Endale M
Ekberg A
Akala HM
Alao JP
Sunnerhagen P
Yenesew A
Erdélyi M
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Four new naphthohydroquinones, named busseihydroquinones A−D (1−4), along with a known homoprenylated dihydronaphthoquinone (5), were isolated from the CH2Cl2/MeOH (1:1) extract of the roots of Pentas bussei. Although the genus Pentas is frequently used by traditional healers for the treatment of malaria, only marginal activities against the chloroquine-sensitive (D6) and the chloroquineresistant (W2) strains of Plasmodium falciparum were observed for the crude root extract and the isolated constituents of this plant.
URI
http://profiles.uonbi.ac.ke/ayenesew/publications/busseihydroquinones-d-roots-pentas-busseihttp://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/44733
http://www.ncbi.nlm.nih.gov/pubmed/22709138
Citation
Yenesew, A. 2012. Busseihydroquinones A-D from the Roots of Pentas bussei. Journal of Natural Products. 75 :1299-1304..Publisher
University of Nairobi Department of Chemestry