Long-term use of permethrin-impregnated nets does not increase Anopheles gambiae permethrin tolerance
Date
1996Author
Vulule, J M
Beach, R F
Atieli, F K
Mount, D L
Roberts, J M
Mwangi, R W
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Previous use of permethrin-impregnated bednets (mosquito nets) and curtains in four Kenyan villages for one year, 1990-91, raised the permethrin LT50 of Anopheles gambiae to 2.4-fold above its baseline value, designated permethrin tolerance (PT), as measured by exposure to 0.25% permethrin-impregnated papers in W.H.O. test-kits. During 1992-93, with ongoing use of permethrin-impregnated nets and curtains, PT regressed slightly compared with the contemporary susceptibility level of An. gambiae from non-intervention villages, to 1.8-fold in 1992 and only 1.6-fold in 1993. Thus the selection pressure of impregnated nets for PT in Angambiae appears to be minimal in our study villages, although the impact of permethrin was demonstrated by a significantly lower parous-rate of Angambiae females in the intervention (63–66%) than in non-intervention (79%) villages, and by reduced malaria transmission (reported elsewhere).
In a selected stock of An. gambiae from the study area, PT did not affect the susceptibility to deltamethrin, fenitrothion, propoxur or DDT. Bioassays described herein provide easy procedures for field-monitoring of mosquito susceptibility/tolerance/resistance to insecticides used for net impregnation in operational programmes.
URI
http://onlinelibrary.wiley.com/doi/10.1111/j.1365-2915.1996.tb00084.x/abstracthttp://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/47968
Citation
Vulule, J. M., Beach, R. F., Atieli, F. K., Mount, D. L., Roberts, J. M. And Mwangi, R. W. (1996), Long-term use of permethrin-impregnated nets does not increase Anopheles gambiae permethrin tolerance. Medical and Veterinary Entomology, 10: 71–79. doi: 10.1111/j.1365-2915.1996.tb00084.xPublisher
University of Nairobi Department of Zoology