Holoprosencephaly in a long-tailed macaque (Macaca fascicularis): A case report

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Date
1994
Author
Tarantal, A.F
Otianga-Owiti, G
Hendrickx, A.G
Type
Article
Language
en
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Abstract
A long-tailed macaque fetus with ethmocephaly, alobar holoprosencephaly, and arhinia is reported. This fetus was exposed to an antiprogestational agent, RU 486 (2.5 mg/kg intramuscular, once daily), during gestational days 15–18. Three hypotheses are proposed to explain these malformations: (1) they are a direct result of drug exposure, (2) they are a secondary effect of treatment and the result of decreased blood supply to the developing embryo due to an incomplete abortion, and (3) they represent a spontaneous occurrence.
URI
http://onlinelibrary.wiley.com/doi/10.1111/j.1600-0684.1994.tb00293.x/abstract
http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/54187
Citation
A.F. Tarantal, G. Otianga-Owiti and A.G. Hendrickx (1994). Holoprosencephaly in a long-tailed macaque (Macaca fascicularis): A case report. Journal of Medical Primatology Volume 23, Issue 6, pages 319–324
Publisher
California Regional Primate Research Center, University of California
 
Department of Veterinary Anatomy, University of Nairobi
 
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