Some Further Fractions Of Arylacetic Acids And Related Compounds With Sodium Hypochlorite

Abstract

In the leactiol1 of arylacetic acids with alkaline sodium hyp och Lorit e it has been shown t.hat the nature of the products depends Oil the substit.uents on the ring. Hhen electron atlac- ling groups arc present. the products arc the next. lower aldehyde and/or carboxylic. acid: the type of product. being det.ermined by the experirnen t aL cond i t i.ons , Whp.n electron releasing groups are present the ring is activated towards substitution by electrop~iJic chlorine to give ch10ro- and dichloro derivatives. In phenylacetic acid itself, contrary to a previous report, we have shown that both oxidat.ion/cleu:rhoxylation and chlorine substitution of the ring pay take place. PYlidyl acetic acids behave in a similar fashion t.o benze~e deriva t ive s bearing e l ec t r on T",itbd~~±-ng groups.