Effect of parasite control on immune response to Newcastle Disease vaccination in village chicken, Mbeere sub county
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Date
2014Author
Kemboi, D C
Chegeh, H W
Bebora, L C
Nyaga, P N
Njagi, L W
Maingi, N
Mbuthia, P G
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
The aim of this study was to determine the effect of parasitism on village chickens’ immune response to Newcastle disease (ND) vaccination. Seventy two chickens, from a population that was confirmed to be infected with ecto- and endo-parasites, from Mbeere District, were bought and divided into 8 groups which were variously treated for parasites: Groups 1 and 8 were controls, while Groups 2 and 5, 3 and 6, 4 and 7 were duplicate treated for endo-parasites only, ecto-parasites only and for both endo- and ecto-parasites, respectively. Groups, 5, 6 and 7 were also vaccinated with ND vaccine; the duplicate unvaccinated groups served as respective controls. Since these birds were also found to carry coccidian, all groups except Group 8 were also treated for coccidiosis; this was to give all the treated groups a baseline start, free of coccidia. After respective vaccination, all the birds were monitored serologically for six weeks; their antibody titres were determined on weekly basis, using hemagglutination inhibition (HI) test.
Upon vaccination, groups 5, 6 and 7 showed a significant rise (P<0.05) in Newcastle disease antibody titer from the start to the end of the experiment compared to the baseline one in the non vaccinated groups 2, 3 and 4. For the vaccinated group, after the 3rd week post vaccination up to the end of the experiment, group 7 had a significantly higher antibody titer (P< 0.05) than the other 2 vaccinated groups 5 and 6. Titres for Groups 1 and 8 continuously dropped over the experimental period. The study has, thus, shown that parasite control resulted in improved immune response to ND by the experimental birds; total parasite treatment giving better results than partial treatments (for ecto- or endo-parasites only). Farmers should, therefore, be advised to practice total parasite control before vaccination
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http://www.lrrd.org/lrrd26/2/kemb26034.htmhttps://profiles.uonbi.ac.ke/pgmbuthia/publications/effect-parasite-control-immune-response-newcastle-disease-vaccination-village
http://hdl.handle.net/11295/65114
Citation
and D. C. Kemboi, H.W. Chegeh BNNMMGLCPN. "Effect of parasite control on immune response to Newcastle Disease vaccination in village chicken, Mbeere sub county." Livestock Research for Rural Development. 2014;Vol 26 (2).Publisher
University of Nairobi