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    Surface Modified Electrode Used In The Electro-analysis Of N-Acetyl P-Aminophenol- A Pharmaceutical Drug

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    Date
    2014
    Author
    Duke, Orata
    Amir, Yusuf
    Nineza, Claire
    Marina, Mukabi
    Damaris, Mbui
    Type
    Article
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    Abstract
    : In this paper we report on the electrochemical behavior of paracetamol or N-acetyl-p-aminophenol. In the electro-analysis bare carbon graphite and bentonite modified working electrode has been used in conjunction with cyclic voltammetry to study its redox properties. The results indicate that, the oxidation and reduction potentials of paracetamol occur at 0.600V and 0.750V. The paracetamol cyclic voltammogram is reversible.From the results obtained we observe that, paracetamol interacts with consumables such tea and milk; metal ions such as CO2+ and Fe2+. It is also shown to interact with vitamin, ferrous fumarate and hydrocortisone. The observed electrochemical behaviour of paracetamol, if replicated at the cellular level, can give insight into its mechanistic and interactive pathways.
    URI
    http://hdl.handle.net/11295/71643
    Citation
    1-Department of Chemistry University of Nairobi Box 30197-00100, Nairobi 2- University of Burundi Bujumbura, Burundi.
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    • Faculty of Agriculture & Veterinary Medicine (FAg / FVM) [5481]

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