Journal Articles: Recent submissions
Now showing items 101-120 of 29992
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Tumor microenvironment of Burkitt lymphoma: different immune signatures with different clinical behavior
(University of Nairobi, 2024)Burkitt lymphoma (BL) is characterized by a tumor microenvironment (TME) in which macrophages represent the main component, determining a distinct histological appearance known as "starry sky" pattern. However, in some ... -
WHO's essential medicines and AWaRe: recommendations on first- and second-choice antibiotics for empiric treatment of clinical infections
(University of Nairobi, 2024)The WHO Model List of Essential Medicines (EML) prioritizes medicines that have significant global public health value. The EML can also deliver important messages on appropriate medicine use. Since 2017, in response to ... -
Two-drug regimens for the treatment of HIV in Africa
(University of Nairobi, 2024)Two-drug regimens for the treatment of HIV are increasingly available. The oral regimen of dolutegravir plus lamivudine is recommended as a preferred option in multiple national guidelines but is not currently included in ... -
Overview of dyslipidemia and metabolic syndrome in myeloproliferative neoplasms
(University of Nairobi, 2024)Myeloproliferative neoplasms (MPNs) occur due to the abnormal proliferation of one or more terminal myeloid cell lines in peripheral blood. Subjects suffering from MPNs display a high burden of cardiovascular risk factors, ... -
Making cities mental health friendly for adolescents and young adults
(University of Nairobi, 2024)Urban life shapes the mental health of city dwellers, and although cities provide access to health, education and economic gain, urban environments are often detrimental to mental health1,2. Increasing urbanization over ... -
Prevalence of all epilepsies in urban informal settlements in Nairobi, Kenya: a two-stage population-based study
(University of Nairobi, 2024)Background: WHO estimates that more than 50 million people worldwide have epilepsy and 80% of cases are in low-income and middle-income countries. Most studies in Africa have focused on active convulsive epilepsy in rural ... -
Acute cholangitis: a state-of-the-art review
(Acute cholangitis: a state-of-the-art review, 2024)Acute cholangitis is a potentially life-threatening bacterial infection of the intra and/or extrahepatic bile ducts. It remains the second and third cause of community-acquired and hospital-acquired bacteremia, respectively, ... -
The prevalence, patterns and factors associated with work related musculoskeletal symptoms among surgical residents in Kenyatta National Hospital, Nairobi, Kenya
(JPPS, 2024-04-19)Background: In the medical sector, surgeons work in an environment that is not ergonomically ideal, and many suffer work-related musculoskeletal symptoms that may result in reduced quality of life, disability, and diminished ... -
Farm production diversity and its influence on diet quality in South Eastern Kenya.
(Informa UK Limited,, 2024-01-27)Agriculture nutrition linkages have long been recognized as a potentially viable pathway of attaining food and nutrition security. However, these insights have started to influence mainstream thinking on agricultural ... -
Assessing determinants of scaling up pathways for adopted CSA Climate Smart Agricultural practices: Evidence from Climate Smart Villages in Nyando Basin, Kenya
(Informa UK Limited,, 2024-03-31)Africa has recently experienced adverse climate changes and has recognized tremendous advancement of numerous Climate Smart Agriculture (CSA) technologies with ability to promote resilience and productivity. However, these ... -
Drivers of climate-smart agricultural technology uptake among smallholder coffee farmers in Kalehe Territory, Democratic Republic of Congo
(Informa UK Limited,, 2024-02-19)Climate-smart agricultural technologies (CSATs) are important for climate change adaptation and mitigation in developing countries. Therefore, it is crucial for farmers to have access to sustainable CSATs to cope with ... -
Farmers’ awareness and perceptions on Newcastle disease in chicken: Evidence from high and low rainfall regions of Kenya
(Informa UK Limited,, 2023-12-04)Newcastle disease (ND) poses a major challenge to Kenyan farmers who raise local chicken in a free-range system. The lack of consistent poultry rearing practices makes it unclear how farmers manage the disease. Insufficient ... -
Role of agricultural extension in learning for uptake and intensification of less-practiced dairy climate-smart practices in Kenya
(Informa UK Limited,, 2024-03-22)The enhanced uptake of dairy climate-smart practices (DCSPs) is important to cushion farmers against the effects of climate change. However, uptake remains low. Besides, there is limited evidence on the learning phase ... -
Grain handling and storage practices of grain traders in Kenya and its implications in reducing food losses
(Informa UK Limited,, 2024-02-08)Post-harvest losses occur during storage mainly due to spills, fungal contamination, and pest damage. Therefore, this study was carried out to evaluate the effect of post-harvest management and sanitation practices by grain ... -
Determinants of the intensity of adoption of climate-smart horticulture practices in Taita-Taveta County, Kenya
(Informa UK Limited, 2024-03-31)horticulture is an important sub-sector of the Kenyan economy that contributes to food and nutrition security as well as a source of income to small-scale farmers. however, the sub-sector is ... -
Planned teacher participation in pedagogy and learner achievement in Secondary Schools in West Pokot Kenya
(2024-04)Planned teacher participation in pedagogy, characterized by the systematic utilization of schemes of work, lesson plans, and diverse teaching methods, are structured frameworks which lay foundation for effective teaching ... -
The potential impact and cost of focusing HIV prevention on young women and men: A modeling analysis in western Kenya
(University of Nairobi, 2024)Objective: We compared the impact and costs of HIV prevention strategies focusing on youth (15-24 year-old persons) versus on adults (15+ year-old persons), in a high-HIV burden context of a large generalized epidemic. Design: ... -
Towards pharmacogenomics-guided tuberculosis (TB) therapy: N-acetyltransferase-2 genotypes among TB-infected Kenyans of mixed ethnicity
(University of Nairobi, 2024)Background: Though persons of African descent have one of the widest genetic variability, genetic polymorphisms of drug-metabolising enzymes such as N-Acetyltransferase-2 (NAT2) are understudied. This study aimed to identify ... -
Typhoid fever in India: A growing concern requiring immediate preventive efforts
(University of Nairobi, 2024) -
Positive and Healthy Living Program Manual Development for Young People Living With HIV at the Comprehensive Care Center at the Kenyatta National Hospital: An Open Pilot Implementation Trial
(University of Nairobi, 2024)Background: Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) remains a great challenge among young people in Kenya. Young people living with HIV are faced with a lot of challenges that are often ...
