Journal Articles: Recent submissions
Now showing items 2781-2800 of 29992
-
Consensus statement: supporting safer conception and pregnancy for men and women living with and affected by HIV
(University of Nairobi, 2017)Safer conception interventions reduce HIV incidence while supporting the reproductive goals of people living with or affected by HIV. We developed a consensus statement to address demand, summarize science, identify ... -
Safety, immunogenicity, and cross-species protection of a plasmid DNA encoding Plasmodium falciparum SERA5 polypeptide, microbial epitopes and chemokine genes in mice and olive baboons.
(University of Nairobi, 2017)Incorporation of biomolecular epitopes to malarial antigens should be explored in the development of strain-transcending malarial vaccines. The present study sought to determine safety, immunogenicity and cross-species ... -
The Highest Common Factor In The Current And Future Information Profession
(university of Nairobi, 2011)Rapid developments in ICT and globalization impinge on the traditional information profession, necessitating a paradigm shift if the profession is to stay relevant in an ever changing environment. This paper acknowledges ... -
Costs of integrating cervical cancer screening at an HIV clinic in Kenya.
(University of Nairobi, 2017)OBJECTIVE: To estimate the societal-level costs of integrating cervical cancer screening into HIV clinics in Nairobi, Kenya. METHODS: A cross-sectional micro-costing study was performed at Coptic Hope Center for ... -
Potential biomarkers associated with discrimination between latent and active pulmonary tuberculosis.
(University of Nairobi, 2017)SETTING: A third of the world's population has latent tuberculous infection (LTBI). Current TB diagnostics used in developing countries are ineffective and are unable to distinguish LTBI from active TB. Identifying ... -
Knowledge, attitudes and practices towards spotted fever group rickettsioses and q fever in Laikipia and Maasai Mara, Kenya.
(University of Nairobi, 2016)Many factors contribute to misdiagnosis and underreporting of infectious zoonotic diseases in most sub-Saharan Africa including limited diagnostic capacity and poor knowledge. We assessed the knowledge, practices and ... -
Simplified paper format for detecting HIV drug resistance in clinical specimens by oligonucleotide ligation.
(University of Nairobi, 2016)Human immunodeficiency virus (HIV) is a chronic infection that can be managed by antiretroviral treatment (ART). However, periods of suboptimal viral suppression during lifelong ART can select for HIV drug resistant (DR) ... -
Reversibility of glomerular renal function decline in hiv-uninfected men and women discontinuing emtricitabine-tenofovir disoproxil fumarate pre-exposure prophylaxis.
(University of Nairobi, 2016)BACKGROUND: Tenofovir disoproxil fumarate (TDF) pre-exposure prophylaxis (PrEP) use is associated with a small but statistically significant decline in estimated glomerular filtration rate (eGFR). We investigated the ... -
Low risk of proximal tubular dysfunction associated with emtricitabine-tenofovir disoproxil fumarate preexposure prophylaxis in men and women.
(University of Nairobi, 2016)OBJECTIVE: Tenofovir disoproxil fumarate (TDF) is associated with proximal tubular dysfunction (tubulopathy) when used in the treatment of human immunodeficiency virus (HIV) infection. We evaluated whether TDF causes ... -
Modeling the Cost-Effectiveness of Home-Based HIV Testing and Education (HOPE) for Pregnant Women and Their Male Partners in Nyanza Province, Kenya.
(University of Nairobi, 2016)INTRODUCTION: Women in sub-Saharan Africa face a 2-fold higher risk of HIV acquisition during pregnancy and postpartum and the majority do not know the HIV status of their male partner. Home-based couple HIV testing for ... -
Brief Report: Sexual Violence Against HIV-Positive Women in the Nyanza Region of Kenya: Is Condom Negotiation an Instigator?
(University of Nairobi, 2017)For people living with HIV, exposure to sexual violence (SV) is associated with decreased adherence to antiretroviral medication, a primary predictor of their survival. Identification of risk factors for SV is a pressing ... -
Time to act-comprehensive abortion care in east Africa.
(University of Nairobi, 2016) -
Risk factors for hypoxia and tachypnea among adolescents with vertically-acquired HIV in Nairobi.
(University of Nairobi, 2017)BACKGROUND: Chronic lung diseases are increasingly recognized complications of vertically-acquired HIV among adolescents in sub-Saharan Africa and may manifest with hypoxia or tachypnea. We sought to determine the ... -
Genital Injury Signatures and Microbiome Alterations Associated With Depot Medroxyprogesterone Acetate Usage and Intravaginal Drying Practices.
(University of Nairobi, 2017)Background.: Increasing evidence suggests depot medroxyprogesterone acetate (DMPA) and intravaginal practices may be associated with human immunodeficiency virus (HIV-1) infection risk; however, the mechanisms are not ... -
A Risk Assessment Tool for Identifying Pregnant and Postpartum Women Who May Benefit From Preexposure Prophylaxis.
(University of Nairobi, 2017)Background: A human immunodeficiency virus (HIV) risk assessment tool for pregnant women could identify women who would most benefit from preexposure prophylaxis (PrEP) while minimizing unnecessary PrEP exposure. Met ... -
Gender-Specific Combination HIV Prevention for Youth in High-Burden Settings: The MP3 Youth Observational Pilot Study Protocol.
(University of Nairobi, 2017)BACKGROUND: Nearly three decades into the epidemic, sub-Saharan Africa (SSA) remains the region most heavily affected by human immunodeficiency virus (HIV), with nearly 70% of the 34 million people living with HIV ... -
Relationship between functional capacity and health-related quality of life of patients with type-2 diabetes.
(University of Nairobi, 2017)AIMS: Physical function is a determinant of survival in chronic diseases, however, little is known about functional capacity (FC) and self-reported health status of patients with type-2 diabetes (T2D). This study ... -
Socioeconomic and Demographic Factors Influencing Feeding Practices, Morbidity Status, and Dietary Intakes of Children Aged 7-24 Months in Rural Uganda.
(University of Nairobi, 2017)The objective of this study was to analyze the nutritional and morbidity patterns of children aged 7-24 months in relationship to household socioeconomic and demographic characteristics. Structured questionnaires and ... -
Microbial Performance of Food Safety Control and Assurance Activities in a Fresh Produce Processing Sector Measured Using a Microbial Assessment Scheme and Statistical Modeling.
(University of Nairobi, 2016)Current approaches such as inspections, audits, and end product testing cannot detect the distribution and dynamics of microbial contamination. Despite the implementation of current food safety management systems, foodborne ... -
Clinician attendance and delivery practices at hospital-based vaginal deliveries in Western Kenya.
(University of Nairobi, 2016)OBJECTIVE: To characterize delivery practices and factors associated with respectful, evidence-based care at a referral hospital in Western Kenya. METHODS: An exploratory observational study used a standardized ...
