Journal Articles: Recent submissions
Now showing items 2781-2800 of 29939
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Isolation of a new β-carboline alkaloid from aerial parts of Triclisia sacleuxii and its antibacterial and cytotoxicity effects.
(University of Nairobi, 2017)A new β-carboline alkaloid named sacleuximine A (1) together with known compounds palmatine (2), isotetrandrine (3), trans-N-feruloyltyramine (4), trans-N-caffeoyltyramine (5), yangambin (6), syringaresinol (7), sesamin ... -
Induction of humoral immune response to multiple recombinant Rhipicephalus appendiculatus antigens and their effect on tick feeding success and pathogen transmission.
(University of Nairobi, 2016)BACKGROUND: Rhipicephalus appendiculatus is the primary vector of Theileria parva, the etiological agent of East Coast fever (ECF), a devastating disease of cattle in sub-Saharan Africa. We hypothesized that a vaccine ... -
Alcohol use and associations with biological markers and self-reported indicators of unprotected sex in human immunodeficiency virus-positive female sex workers in Mombasa, Kenya.
(University of Nairobi, 2016)BACKGROUND: Studies of alcohol use and sexual behavior in African populations have primarily been cross-sectional, used nonvalidated measures of alcohol use, or relied on self-reported sexual risk endpoints. Few have ... -
Anthocyanin Accumulation in Muscadine Berry Skins Is Influenced by the Expression of the MYB Transcription Factors, MybA1, and MYBCS1.
(University of Nairobi, 2017)The skin color of grape berry is very important in the wine industry. The red color results from the synthesis and accumulation of anthocyanins, which is regulated by transcription factors belonging to the MYB family. The ... -
Influence of cattle on browsing and grazing wildlife varies with rainfall and presence of megaherbivores.
(University of Nairobi, 2017)In many savanna ecosystems worldwide, livestock share the landscape and its resources with wildlife. The nature of interactions between livestock and wildlife is a subject of considerable interest and speculation, yet ... -
Environmental predictors of bovine Eimeria infection in western Kenya.
(University of Nairobi, 2017)Eimeriosis is caused by a protozoan infection affecting most domestic animal species. Outbreaks in cattle are associated with various environmental factors in temperate climates but limited work has been done in tropical ... -
Antifungal activity of essential oil of eucalyptus camaldulensis dehnh. Against selected fusarium spp.
(University of Nairobi, 2017)The objective of this study was to evaluate the antifungal activity of essential oil (EO) of Eucalyptus camaldulensis Dehnh. against five Fusarium spp. commonly associated with maize. The essential oil had been extracted ... -
The socio-economic drivers of bushmeat consumption during the West African Ebola crisis.
(University of Nairobi, 2017)Bushmeat represents an important source of animal protein for humans in tropical Africa. Unsustainable bushmeat hunting is a major threat to wildlife and its consumption is associated with an increased risk of acquiring ... -
Temperature-dependent phenology of Plutella xylostella (Lepidoptera: Plutellidae): Simulation and visualization of current and future distributions along the Eastern Afromontane.
(University of Nairobi, 2017)There is a scarcity of laboratory and field-based results showing the movement of the diamondback moth (DBM) Plutella xylostella (L.) across a spatial scale. We studied the population growth of the diamondback moth (DBM) ... -
Lay knowledge and management of malaria in Baringo county, Kenya.
(University of Nairobi, 2016)BACKGROUND: Malaria, a disease caused by protozoan parasites of the genus Plasmodium and transmitted by female anopheline mosquitoes, is a major cause of morbidity, mortality and loss in productivity in humans. Baringo ... -
Ecological niche modelling of Rift Valley fever virus vectors in Baringo, Kenya.
(University of Nairobi, 2017)BACKGROUND: Rift Valley fever (RVF) is a vector-borne zoonotic disease that has an impact on human health and animal productivity. Here, we explore the use of vector presence modelling to predict the distribution of RVF ... -
Understanding the acceptability and adherence to paediatric antiretroviral treatment in the new formulation of pellets (LPV/r): the protocol of a realist evaluation.
(University of Nairobi, 2017)BACKGROUND: Improving access to paediatric HIV treatment requires both large-scale treatment programmes and medication that is adapted to infants and children's needs. The WHO recommends lopinavir/ritonavir as first-line ... -
Water Stress Tolerance of Six Rangeland Grasses in the Kenyan Semi-arid Rangelands
(University of Nairobi, 2015)This study evaluated six grass species in terms of water stress responses by visual quality and living ground cover attributes and the recovery responses post water stress grown at 80, 50, 30% field capacity soil moisture ... -
Preoperative prediction of the size of pure ductal carcinoma in situ using three imaging modalities as compared to histopathological size: does magnetic resonance imaging add value?
(University of Nairobi, 2017)PURPOSE: The purpose of this study was to evaluate whether magnetic resonance imaging (MRI) and ultrasonography add value to traditional mammography in an Asian population with ductal carcinoma in situ (DCIS). METHODS: Data ... -
Mass mosquito trapping for malaria control in western Kenya: study protocol for a stepped wedge cluster-randomised trial.
(University of Nairobi, 2016)BACKGROUND: Increasing levels of insecticide resistance as well as outdoor, residual transmission of malaria threaten the efficacy of existing vector control tools used against malaria mosquitoes. The development of ... -
In vitro antimycobacterial activity and toxicity of eight medicinal plants against pathogenic and nonpathogenic mycobacterial strains.
(University of Nairobi, 2016)Tuberculosis (TB) caused by Mycobacterium tuberculosis remains a serious public health challenge towards which new hits are urgently needed. Medicinal plants remains a major source of new ligands against global infectious ... -
Development of High Protein and Vitamin A Flakes from Sweet Potato Roots and Leaves
(University of Nairobi, 2015)Sweet potato ( Ipomoea batatas ) is one of the most important, versatile and unexploited crops in Kenya. The crop is well adapted to smallholder farming systems, inexpensive to produce, relativ e- ly ... -
Antimalarial pyrido[1,2-a]benzimidazoles: lead optimization, parasite life cycle stage profile, mechanistic evaluation, killing kinetics, and in vivo oral efficacy in a mouse model.
(University of Nairobi, 2017)Further structure-activity relationship (SAR) studies on the recently identified pyrido[1,2-a]benzimidazole (PBI) antimalarials have led to the identification of potent, metabolically stable compounds with improved in vivo ... -
A Review of Occurrence of Glycoalkaloids in Potato and Potato Products
(University of Nairobi, 2016)There has been increasing consumption of potato products such as French fries and crisps in most countries as a result of lifestyle change in both developed and developing countries. Due to their generally pleasurable taste ... -
Prevalent neuropathy in a cohort of HIV-infected Kenyan sex workers using antiretroviral drugs.
(University of Nairobi, 2016)INTRODUCTION: Several risk factors including stavudine and age have been strongly associated with polyneuropathy. However, conflicting data exist on height as an independent risk factor in polyneuropathy. The objective ...
