Journal Articles: Recent submissions
Now showing items 901-920 of 29939
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Phytochemical Analysis and Establishment of Embryogenic Cell Suspension and Agrobacterium-mediated Transformation for Farmer Preferred Cultivars of West African Plantain (Musa spp.)
(University of Nairobi, 2020)Banana and plantain are among the foremost staple food crops providing food and livelihood to over 500 million people in tropical countries. Despite the importance, their production is hampered due to several biotic and ... -
Comparative in silico study of congocidine congeners as potential inhibitors of African swine fever virus
(University of Nairobi, 2019)African swine fever virus (ASFV) infection is fatal in domesticated pigs, with a mortality rate approaching 100%. This may result in economic losses and threats to food security. Currently, there are no approved vaccines ... -
Risk factors for the incursion, spread and persistence of the foot and mouth disease virus in Eastern Rwanda
(University of Nairobi, 2020)Background: Identification of risk factors is crucial in Foot-and-mouth disease (FMD) control especially in endemic countries. In Rwanda, almost all outbreaks of Foot-and-Mouth Disease Virus (FMDV) have started in Eastern ... -
Two novel lignans derivatives and two fusicoccane diterpenoids from whole plant of Hypoestes verticillaris (L.f.) Sol. ex Roem. & Schult
(University of Nairobi, 2019)Bioassay-guided screening of Hypoestes verticillaris whole plant CH2Cl2:MeOH (1:1) extract for anti-plasmodial activity yielded four new compounds: two lignans 2, 6-dimethoxysavinin (1), 2,6-dimethoxy-(7E)-7,8-dehydrohel ... -
Multiple Cytokines Elevated in Patients with Keloids: Is It an Indication of Auto-Inflammatory Disease?
(University of Nairobi, 2021)Background Inflammation seems to play a major role in the pathophysiology of keloids. However, the role of cytokines in keloid pathophysiology has not been fully evaluated with only a few cytokines studied. We undertook ... -
Rapid Screening using GIBEX Screens-to-nature System of Ethnomedicinal Plants from Ngong Forest, Kenya for Potency against Infectious Diseases and Antioxidant Activities: A Qualitative Study
(University of Nairobi, 2019)Introduction: Plants from Kenyan flora are traditionally used to manage a number of ailments including; chronic and infectious disease, to bolster the body immunity and for general health protections. The current investigation ... -
Cancer and COVID-19 Experiences at African Cancer Centers: The Silver Lining.
(University of Nairobi, 2021)PURPOSE The COVID-19 pandemic significantly disrupted cancer care in Africa, further exposing major health disparities. This paper compares and contrasts the experiences of 15 clinicians in six different African cancer ... -
Oleanolic Acid and other Compounds Isolated from Cordia africana Lam which Inhibit Vancomycin Resistant Enterococcus
(University of Nairobi, 2019)ABSTRACT Introduction: Treatment of microbial infections has become complicated due to increased resistance of microbes to the current drugs. The current study investigates crude extracts and seven compounds from root ... -
Antiplasmodial Biflavanones from the Stem Bark of Garcinia buchananii Engl.
(University of Nairobi, 2019)Introduction: Plants of the genus Garcinia are traditionally used treat a range of infectious and non-infectious diseases. Garcinia species are reported to have been shown to have a range of biological activities including ... -
Antiproliferative Properties of Labdane Diterpenoids from Croton sylvaticus Hochst against Drug Sensitive and Resistant Leukemia cell lines
(University of Nairobi, 2019)Background: Cancer treatment failure is majorly attributed to the emergency of multi-drug resistance of cancer cells towards most conventional drugs used in chemotherapy hence the need for more active principles with less ... -
sssHigh seroprevalence of SARS-CoV-2 but low infection fatality ratio eight months after introduction in Nairobi, Kenya.
(Elsevier Ltd, 2021)Background: The lower-than-expected COVID-19 morbidity and mortality in Africa has been attributed to multiple factors, including weak surveillance. We estimated the burden of SARS-CoV-2 infections eight months into the ... -
Effect of on-farm testing on adoption of banana production technologies among smallholder farmers in Meru region, Kenya.
(Emerald Publishing Limited, 2021)Purpose The purpose of this paper is to investigate the effect of on-farm testing on the adoption of banana production technologies among smallholder farmers in the Meru region, Kenya. Design/methodology/approach The ... -
Anti-leishmanial activity of some surface compounds of Tarchonanthus camphoratus
(University of Nairobi, 2019)Background: The World Health Organization recognizes leishmaniasis as a major tropical disease with no effective vaccine against it. Chemotherapy, the only effective way to treat all forms of the disease, is toxic and ... -
In vitro Antiplasmodial and Cytotoxic activity of Three Medicinal Plants used Traditionally for Treatment of Malaria
(University of Nairobi, 2020)Introduction: Reports of emergence of Artemisinin Combination Therapies (ACTs) resistant malaria parasites in Greater Mekong region and Equatorial Guinea, is a strong reason necessitating increased efforts to discover new ... -
Two new flavonoids from Dracaena usambarensis Engl.
(University of Nairobi, 2020)Investigations of the root extract of Dracaena usambarensis Engl. for anticancer principles led to the characterization of one new homoisoflavonoid, (3S)-3,4ʹ,5,6-tetrahydroxy-7-methoxyhomoisoflavanone (1) and a new ... -
The Dynamics of Culture on Environmental Sustainability: a Case of Central Africa
(University of Nairobi, 2018)Indigenous African socio-cultural practices are distinguished by complex and diverse variations of evolving attitudes and behaviours that play a significant role in the development and conservation or depletion of the ... -
A Cultural Paradigm Shift in Central Africa: Sociocultural Determinants and Cultural Dimensions
(University of Nairobi, 2019)Human beings have evolved to coexist via a transformational context that incites constant adaptation of culture to social, environmental, and economic developments in order to sustain existence. This study aims to characterise ... -
Short-term Casting Activity of Earthworm Pontoscolex Corethrurus Oligochaeta- Glossoscolecidae After Biochar Additions
(University of Nairobi, 2020)Conversion of forests to cultivated farms through slash-and-burn or chop-and-char practices often results in rapid loss of soil organic matter (SOM) or conversion of inherent SOM into pyrogenic organic matter (PyOM). ... -
An Assessment of the Implications of Alternative Scales of Communal Land Tenure Formalization in Pastoral Systems
(University of Nairobi, 2020)Pastoralism faces diverse challenges, that include, among others, land tenure insecurity, that has necessitated the need to formalize land rights. Some governments have started regularizing rights for privately owned land, ... -
What Is the Appropriate Age Range of Individuals to Be Included in a Survey to Estimate the Prevalence of Trachomatous Trichiasis?
(University of Nairobi, 2011)Introduction A survey to determine the prevalence of trachomatous trichiasis (TT) requires a large sample size and the recommended participant age is ≥15 years. This study sought to establish the appropriate age range of ...
