Prevalence of hyperglycemia and associated risk factors in neonates with sepsis at Kisii level five hospital

Abstract

Background The highest proportion of under five mortality occurs in the neonatal period with a global estimation of 4 million infants dying annually in the first four weeks of life .The main causes of death are prematurity- 28%, neonatal infections-26% and asphyxia-23%. The neonatal mortality rate in Kenya is 31/1000 live births with neonatal sepsis contributing significantly to the high neonatal mortality rate. Neonatal sepsis results in metabolic derangements. These include hyperglycemia which is associated with high mortality rates. Other deleterious effects include impaired immunologic function, osmotic diuresis with electrolyte imbalances, intracranial hemorrhage and prolonged hospital stay. Objectives Primary Objectives To determine the prevalence of hyperglycemia in neonates with sepsis admitted at Kisii Level 5 Hospital. Secondary Objective To determine the risk factors associated with hyperglycemia in neonates with sepsis admitted at Kisii Level 5 Hospital. To determine the mortality of neonates with hyperglycemia in sepsis at Kisii Level 5 Hospital.