Browsing Faculty of Science & Technology (FST) by Author "GAKUNJU, DMN"

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    • Potent Antimalarial Activity of the Alkaloid Nitidine, Isolated from a Kenyan Herbal Remedy 

      GAKUNJU, DMN; MBERU, EK; DOSSAJI, SF; GRAY, AI; WAIGH, RD; WATERMAN, PG; WATKINS, WM (Ministry of Health, KenyaThe Wellcome Trust Research LaboratoriesThe National Museums of Kenya,Kenya Medical Research InstituteDepartment of Pharmaceutical Sciences, University of StrathclydeDepartment of Pharmacology and Therapeutics, University of Liverpool, 1995)
      Bioassay-guided fractionation of extracts of Toddalia asiatica, a plant used by the Pokot tribe of Kenya to treat fevers, has yielded the alkaloid nitidine as the major antimalarial component. Fractions containing nitidine ...