Browsing Faculty of Health Sciences (FHS) by Subject "5-fluorouracil"
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Evaluation of dihydropyrimidine dehydrogenase activity in South-west Asian, Kenyan and Ghanaian populations
(Department of Clinical Medicine and Therapeutics, 2000-09)AIMS: Dihydropyrimidine dehydrogenase (DPD) reduces endogenous pyrimidines and therapeutic analogues such as the anticancer agent 5-fluorouracil (5FU). Among Caucasian populations DPD activity is highly variable and subject ...