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Now showing items 10271-10280 of 10378
Economics of East Coast fever: a literature review
(University of Nairobi, 2023)
East Coast fever (ECF) is a cattle disease caused by a protozoan parasite called Theileria parva (T. parva). Theileria parva is transmitted among cattle by ticks. It is endemic in parts of central, eastern, and southern ...
Breast Cancer Management in the Era of Covid-19; Key Issues, Contemporary Strategies, and Future Implications
(University of Nairobi, 2023)
During the COVID-19 pandemic, several priority diseases were not getting sufficient attention. Whilst breast cancer is a fatal disease affecting millions worldwide, identification and management of these patients did not ...
Validation of the English and Swahili Adaptation of the Patient Health Questionnaire-9 for Use Among Adolescents in Kenya
(University of Nairobi, 2023)
Purpose: Our study aimed to validate culturally adapted English and Swahili versions of the Patient Health Questionnaire-9 (PHQ-9) for use with adolescents in Kenya. Criterion validity was determined with clinician-administered ...
Prevalence of non-alcoholic fatty liver disease in overweight and obese children seeking ambulatory healthcare in Nairobi, Kenya
(University of Nairobi, 2023)
Background: While linked to obesity and associated with an increased cardiovascular morbidity, non-alcoholic fatty liver disease (NAFLD) is an often-asymptomatic cause of chronic liver disease in children. Early detection ...
Quality of inpatient paediatric and newborn care in district hospitals: WHO indicators, measurement, and improvement
(University of Nairobi, 2023)
Poor-quality paediatric and neonatal care in district hospitals in low-income and middle-income countries (LMICs) was first highlighted more than 20 years ago. WHO recently developed more than 1000 paediatric and neonatal ...
Assessment of gestational age at antenatal care visits among Kenyan women to inform delivery of a maternal respiratory syncytial virus (RSV) vaccine in low- and middle-income countries
(University of Nairobi, 2023)
Background: Maternal respiratory syncytial virus (RSV) vaccines that are likely to be implementable in low- and middle-income countries (LMICs) are in final stages of clinical trials. Data on the number of women presenting ...
Delayed breast cancer presentation, diagnosis, and treatment in Kenya
(University of Nairobi, 2023)
Purpose: In this mixed-methods study, we evaluated the factors that contribute to delayed breast cancer (BC) diagnosis and treatment at a Kenyan hospital.
Methods: Individuals with a diagnosis of BC, either as a referral ...
Evolutionary mismatch and the role of GxE interactions in human disease
(University of Nairobi, 2023)
Globally, we are witnessing the rise of complex, non-communicable diseases (NCDs) related to changes in our daily environments. Obesity, asthma, cardiovascular disease, and type 2 diabetes are part of a long list of ...
The role of partners, parents and friends in shaping young women's reproductive choices in Peri-urban Nairobi: a qualitative study
(University of Nairobi, 2023)
Background: Contraceptive use among young women in Nairobi remains low despite high general knowledge of family planning (FP) methods. This paper draws on social norms theory to explore the role of key influencers (partners, ...
Challenges and Opportunities in the Genetic Analysis of Inherited Retinal Dystrophies in Africa, a Literature Review
(University of Nairobi, 2023)
Inherited retinal dystrophies (IRDs) are a global problem that is largely unaddressed, especially in Africa. Black indigenous Africans are rarely represented in research that develops genetic tests and genetic therapies ...