Faculty of Health Sciences (FHS): Recent submissions
Now showing items 1341-1360 of 10417
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Room temperature stable carbetocin for the prevention of postpartum haemorrhage during the third stage of labour in women delivering vaginally: study protocol for a randomized controlled trial
(2016)Background Postpartum haemorrhage (PPH) is the leading cause of maternal mortality in low-income countries and contributes to nearly a quarter of maternal deaths globally. The current available interventions for prevention ... -
Uptake and Effectiveness of a Trivalent Inactivated Influenza Vaccine in Children in Urban and Rural Kenya, 2010 to 2012.
(2016)In Africa, recent surveillance has demonstrated a high burden of influenza, but influenza vaccine is rarely used. In Kenya, a country with a tropical climate, influenza has been shown to circulate year-round, like in other ... -
Changes in Vaginal Microbiota and Immune Mediators in HIV-1-Seronegative Kenyan Women Initiating Depot Medroxyprogesterone Acetate
(2016)Background: Depot medroxyprogesterone acetate (DMPA) is associated with HIV acquisition. We studied changes in vaginal microbiota and inflammatory milieu after DMPA initiation. Methods: In a cohort of HIV-negative Kenyan ... -
Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort.
(2016)Broadly neutralizing antibodies (bnAbs) are thought to be a critical component of a protective HIV vaccine. However, designing vaccines immunogens able to elicit bnAbs has proven unsuccessful to date. Understanding the ... -
Schistosoma haematobium and soil-transmitted Helminths in Tana Delta District of Kenya: infection and morbidity patterns in primary schoolchildren from two isolated villages
(2016)Schistosomes and soil-transmitted helminths (STH) (hookworm, Trichuris trichiura and Ascaris lumbricoides) are widely distributed in developing countries where they infect over 230 million and 1.5 billion people, respectively. ... -
Red cell allo- and autoimmunisation in transfused sickle cell and cancer patients in Kenyatta National Hospital, Nairobi, Kenya
(2015)Background: Currently, no data are available on the prevalence of red blood cell (RBC) antibody formation amongst Kenyan patients with multiple transfusion needs, such as patients with sickle cell disease (SCD) or ... -
Glycemic Control in Kenyan Children and Adolescents with Type 1 Diabetes Mellitus
(2015)Background. Type 1 diabetes mellitus (T1DM) is the most common endocrine disorder in children and adolescents worldwide. While data about prevalence, treatment, and complications are recorded in many countries, few data ... -
Clinical pharmacokinetic properties of magnesium sulphate in women with pre-eclampsia and eclampsia
(2016)Background The pharmacokinetic basis of magnesium sulphate (MgSO4) dosing regimens for eclampsia prophylaxis and treatment is not clearly established. Objectives To review available data on clinical pharmacokinetic ... -
Knowledge, attitudes and practices of infertile couples on male participation in infertility management at the Kenyatta National Hospital
(KMA, 2015)Objective: To determine knowledge, attitudes and practices of infertile couples on male involvement in the management of infertility. Design: Hospital based cross-sectional study. Setting: Kenyatta National Hospital, ... -
Urine neutrophil gelatinase-associated lipocalin in asphyxiated neonates: a prospective cohort study
(Springer, 2015)Acute kidney injury (AKI) is the most common complication of perinatal asphyxia. Recent research indicates that urine neutrophil gelatinase-associated lipocalin (NGAL) is an early marker for AKI; yet, there is a paucity ... -
Differential immune responses in mice infected with the tissue-dwelling nematode Trichinella zimbabwensis
(2015)To improve diagnostic tools, immunotherapies and vaccine development for trichinellosis surveillance and control there is a need to understand the host immune responses induced during infection with Trichinella zimbabwensis, ... -
Cortisol levels and short term outcome in hiv infected patients with sepsis in Kenyatta Hospital
(2009)Introduction Adrenal insufficiency occurs in Human immunodeficiency virus (HIV)/ Acquired Immunodeficiency Syndrome (AIDS) and causes morbidity and mortality in HIV patients. Objective To determine cortisol levels and ... -
The prevalence of active pulmonary tuberculosis among prisoners at Kamiti Maximum Security Prison, Kenya.
(2005)Background: Tuberculosis (TB) is one of the leading causes of mortality in Kenyan prisons. No systematic studies have been done to determine the prevalence of TB in this population. This study set out to determine the ... -
Perioperative Management of Patients with Psoriatic Arthritis: Case Report and Literature Review
(2015)Background: This paper aims to explore the assessment of patients with psoriatic arthritis before undergoing orthopaedic surgery. Perioperative assessment starts with early diagnosis of the patient’s medical condition, ... -
Clinical and socio-demographic profile of patients on treatment for osteoporosis in Nairobi, Kenya
(2015)Background: Osteoporosis is a chronic, progressive disease of multifactorial aetiology and one of the most common metabolic bone diseases worldwide. There is a paucity of data on osteoporosis in Africa as it’s generally ... -
Disorders of sexual differentiation as seen at Kenyatta National Hospital
(KMA, 2016)Background: Disorders of sexual differentiation (DSD) are a group of congenital anomalies characterised by discordance between genetic, gonadal and phenotypic sex. There has been remarkable evolution in management over the ... -
Capacity of non-tertiary Kenyan health facilities selected for decentralised dental training
(KMA, 2016)Objective: To determine the capacity of six non-tertiary Kenyan hospitals enrolled as sites for decentralised dental education. Design: A descriptive cross-sectional study. Setting: The Dental departments of six ... -
Diffuse idiopathic skeletal hyperostosis: case report and literature review
(2016)Background: Diffuse Idiopathic Skeletal Hyperostosis (DISH) is a common disorder of unknown aetiology that is characterized by back pain and spinal stiffness. Diffuse idiopathic skeletal hyperostosis is a common disease, ...
