Faculty of Health Sciences (FHS): Recent submissions
Now showing items 1681-1700 of 10417
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Comprehensive global evolution of intramedullary nailing of diaphyseal fractures
(2009)The treatment of midshaft fractures of the long bones has significantly evolved in the last 150 years. This paper will trace the timeline and evaluate the treatment of these fractures which has evolved through from ... -
Total hip replacements at Kikuyu Hospital, Kenya
(2010)Background: Total joint arthroplasty is a highly effective procedure that is frequently performed in elderly patients. This is not so in the third world and is not frequently performed. Total hip replacement (THR) relieves ... -
Early functional outcome of distal femoral fractures at Kenyatta National Hospital and Kikuyu Hospital
(2013)Background: Distal femoral fractures account for 4% to 7% of all femoral fractures. They cause considerable morbidity and mortality, especially in the elderly. Locally they occur mainly in the young socio-economically ... -
Strong association between human and animal brucella seropositivity in a linked study in Kenya, 2012-2013.
(University of Nairobi, 2014)Brucellosis is a common bacterial zoonotic infection but data on the prevalence among humans and animals is limited in Kenya. A cross-sectional survey was conducted in three counties practicing different livestock production ... -
Increased levels of inflammatory cytokines in the female reproductive tract are associated with altered expression of proteases, mucosal barrier proteins, and an influx of HIV-susceptible target cells.
(University of Nairobi, 2015)Elevated inflammatory cytokines (EMCs) at mucosal surfaces have been associated with HIV susceptibility, but the underlying mechanisms remain unclear. We characterized the soluble mucosal proteome associated with elevated ... -
The Involvement of Human Cyr61 in Heregulin Induction of Breast Tumor Progression
(2003)This fellowship, originally granted to Dr. M. Tsai and later transferred to Dr. H. Oketch-Rabah in the laboratory of Dr. R. Lupu, was initially concerned with the role of the cytokine heregulin, in the regulation of hormone ... -
Malaria N 9-Subject N 15
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Mondia whitei, a medicinal plant from Africa with aphrodisiac and antidepressant properties: a review
(2012)This paper reviews the literature concerning the ethnobotany, phytochemistry, and pharmacology of Mondia whitei, which is also known as Mondia whytei, African ginger or simply as mondia. Mondia is used in many parts of ... -
A New Class of Spermidine-Derived Alkaloids
(2003)Four new alkaloids, dovyalicins A−D, were isolated from Dovyalis macrocalyx. Their structures were established by two-dimensional COSY, NOESY, HSQC, and HMBC NMR experiments as well as chiroptical methods. The compounds, ... -
Dovyalicin-Type Spermidine Alkaloids from Dovyalis Species
(2006)Phytochemical investigations of Dovyalis abyssinica, D. hebecarpa, and D. macrocalyx revealed two new spermidine-type alkaloids, dovyalicin E (3) and dovyalicin F (4), along with the previously described dovyalicin A (1), ... -
Antimalarial Activity of Some Plants Traditionally used in Meru district of Kenya
(2007)Ten plant extracts commonly used by the Meru community of Kenya were evaluated for the in vitro antiplasmodial, in vivo antimalarial, cytotoxicity and animal toxicity activities. The water and methanol extracts of Ludwigia ... -
Retinoblastoma in Kenya: survival and prognostic factors
(University of Nairobi, 2015-03)BACKGROUND: In industrialized nations a curative therapy of retinoblastoma can be achieved in a large number of patients due to timely diagnosis and therapy. In developing countries the survival rates are much lower and ... -
Antimicrobial Activity, Toxicity and Phytochemical Screening of Four Medicinal Plants Traditionally Used in Msambweni District, Kenya
(2014)This study was designed to evaluate the antimicrobial activity, toxicity and phytochemical composition of organic and aqueous crude extracts of Zanthoxylum chalybeum Engl. (Rutaceae), Adansonia digitata L. (Bombacaceae), ... -
Elastic fibre system in the shaft of adult human penis
(University of Nairobi, 2015)Elastic fibres play a central role in functioning of the penis. Detailed animal studies have quantified elastic and collagen fibre content in rat and rabbit penis. Though rabbit model i s similar ... -
Khat (Catha edulis)-induced apoptosis is inhibited by antagonists of caspase-1 and-8 in human leukaemia cells
(2004)Khat chewing is a widespread habit that has a deep-rooted sociocultural tradition in Africa and the Middle East. The biological effects of khat are inadequately investigated and controversial. For the first time, we show ...
