Faculty of Health Sciences (FHS): Recent submissions
Now showing items 2521-2540 of 10418
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Microsatellite typing reveals strong genetic structure of Schistosoma mansoni from localities in Kenya.
(KMA, 2006)Genetic diversity and population structure of seven populations of Schistosoma mansoni sampled in Kenya were assessed using five microsatellite markers. The mean number of alleles per locus, expected heterozygosity in ... -
Microbiological quality and safety of Rastrineobola argentea retailed in Kisumu town markets, Kenya.
(KMA, 2008)OBJECTIVE: To investigate faecal contamination and safety of Rastrineobola argentea sold in retail markets in Kisumu town. DESIGN: This was a repeated cross sectional study and based on random sampling. Setting: Kisumu ... -
Urinary soluble egg antigen levels in Schistosoma haematobium infection in relation to sex and age of Kenyan schoolchildren following praziquantel treatment.
(Oxford Journals, 2009)Schistosoma haematobium soluble egg antigen (SEA) secreted in urine can be assayed to determine egg tissue load and hence morbidity in infected individuals. A cohort of 158 infected children aged 4-18 years was followed-up ... -
Reference values for some renal function parameters for adult population in north-rift valley, kenya.
(PMC, 2012)A population based, cross-sectional study was carried out at Moi Teaching and Referral Hospital in collaboration with the Regional Blood Transfusion Center, North Rift. 367 participants (211 males and 156 females) were ... -
Regular Male Partners of Female Sex Workers from Nairobi, Kenya: High Risk Partnerships with Important Implications for HIV Transmission (
(University of NairobiSchool of Medicine, 2012) -
A flexible joint modeling framework for longitudinal and time-to-event data with overdispersion.
(Sage PublicationsCollege of Health Sciences, 2013)We combine conjugate and normal random effects in a joint model for outcomes, at least one of which is non-Gaussian, with particular emphasis on cases in which one of the outcomes is of survival type. Conjugate random ... -
Impact of asymptomatic Herpes simplex virus-2 infection on T cell phenotype and function in the foreskin
(University of NairobiDepartment of Medicine, 2012-06)Herpes simplex virus type 2 (HSV-2) increases the risk of HIV acquisition in men and overall CD4 T cell density in the foreskin. Using tissues obtained during routine male circumcision, we examined the impact of HSV-2 on ... -
No difference in keratin thickness between inner and outer foreskins from elective male circumcisions in Rakai, Uganda.
(University of NairobiSchool of Medicine, Chicago,, 2012)It has been hypothesized that increased HIV acquisition in uncircumcised men may relate to a more thinly keratinized inner foreskin. However, published data are contradictory and potentially confounded by medical indications ... -
HIV infection in uncircumcised men is associated with altered CD8 T cell function but normal CD4 T cell numbers in the foreskin
(School of Medicine, 2013-11)Background. HIV-infected (HIV+) men are more susceptible to sexually transmitted infections (STIs), and may also become superinfected by HIV. We hypothesized that HIV induces immune alterations in the foreskin that may ... -
Too young to take over: - the hidden face of HIV/AIDS : orphans and vulnerable children from a Kenyan perspective
(University of NairobiSchool of Medicine, 2004) -
Treatment of Chacroid with a 5-day Low Dose Erythromycin Regimen.
(University of NairobiCollege of Health Science, 1992-07) -
Mucosal Th17 cell function is altered during HIV infection and is an independent predictor of systemic immune activation.
(University of NairobiDepartment of Medical Microbiology, 2013-09)Mucosal Th17 cells maintain the gut epithelial barrier and prevent invasion by luminal bacteria through a delicate balance of immunosuppressive and proinflammatory functions. HIV infection is characterized by mucosal Th17 ... -
A joint model for longitudinal continuous and time-to-event outcomes with direct marginal interpretation
(WileyCollege of Health Sciences, 2013)Joint modeling of various longitudinal sequences has received quite a bit of attention in recent times. This paper proposes a so-called marginalized joint model for longitudinal continuous and repeated time-to-event outcomes ... -
The role of dendritic cells in driving genital tract inflammation and HIV transmission risk: Are there opportunities to intervene?
(University of NairobiDepartment of Medical Microbiology, 2013-11-26)Effective prevention of new HIV infections will require an understanding of the mechanisms involved in HIV acquisition. HIV transmission across the female genital tract is the major mode of new HIV infections in sub-Saharan ... -
Phase 2A dose and route study of a DNA prime MVA boost vaccine candidate
(University of NairobiSchool of Medicine, 2005) -
Male, Mobile, and Moneyed: Loss to Follow-Up vs. Transfer of Care in an Urban African Antiretroviral Treatment Clinic.
(University of NairobiDepartment of Medical Microbiology,, 2013-10)OBJECTIVES: The purpose of this study was to analyze characteristics, reasons for transferring, and reasons for discontinuing care among patients defined as lost to follow-up (LTFU) from an antiretroviral therapy (ART) ... -
Pharmacokinetics and clinical effects of phenytoin in children with malaria and convulsions
(University of NairobiSchool of Medicine, 2002) -
A qualitative and quantitative study of medical leadership and management: experiences, competencies, and development needs of doctor managers in the United Kingdom
(University of NairobiSchool of Public Health, 2011)Health-care systems need strong leadership if they are to be sustainable and responsive to the health needs of the future. There is little empirical and theoretical literature about how medical managers conceptualize ... -
Occurrence of adverse drug reactions associated with highly active anti-retroviral therapy at Mbagathi District Hospital, Nairobi, Kenya
(University of NairobiSchool of Public Health, 2013)Background: Life-saving highly active anti-retroviral therapy (HAART) has been accompanied by the challenge of incident adverse drug reactions (ADRs). Locally generated data is scanty, inadequately documented, and therefore ... -
Africa: the changing environment and health
(University of NairobiSchool of Public Health, 1992)Like other developing areas of the world, Africa is undergoing social, political, and economic changes. These developmental changes have provided important benefits, but have also produced significant impacts on the ...
