Faculty of Health Sciences (FHS): Recent submissions
Now showing items 4521-4540 of 10418
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Debating the quality and performance of health systems at a global level is not enough, national debates are essential for progress
(Department of Paediatrics & Child Health, 2008-04) -
The Epidemiology of Human Rotavirus Associated with Diarrhoea in Kenyan Children: A Review
(Department of Paediatrics & Child Health, 2008)Rotavirus gastroenteritis still remains a major cause of morbidity and mortality among young children in developing countries, with ∼150 000–200 000 deaths occurring annually in sub-Saharan Africa. We reviewed papers ... -
A Multifaceted Intervention to Implement Guidelines and Improve Admission Paediatric Care in Kenyan District Hospitals: A Cluster Randomised Trial
(Department of Paediatrics & Child Health, 2011)In developing countries referral of severely ill children from primary care to district hospitals is common, but hospital care is often of poor quality. However, strategies to change multiple paediatric care practices in ... -
An international perspective on child day-care health
(Department of Paediatrics & Child Health, 1994-12-01)If we are committed to the health and development of children, we need to recognize that the vast majority of the world's women are working women. In Africa, 80% of the women are actively engaged in economic activities ... -
Fanconi's anaemia; Chromosome breakage in a large African family
(Department of Paediatrics & Child Health, 1980-12)A boy with Fanconi's anaemia (FA), his parents and nine living brothers and sisters were serially investigated during a period of 5 years. As the illness progressed the propositus showed high, successively increasing ... -
Hospital autonomy: The experience of Kenyatta National Hospital
(Department of Paediatrics & Child Health, 1999-06)An increasing number of countries are exploring the introduction or expansion of autonomous hospitals as one of the numerous health reforms they are introducing to their health system. Hospital autonomy is one of the forms ... -
III. Albendazole in the treatment of inoperable hydatid disease in Kenya—a report on 12 cases
(University of NairobiDepartment of Medicine, 1986)The results of treatment of 12 cases of inoperable hydatid disease in Kenya using albendazole at a dose of 10 mg/kg body-weight for eight weeks are reported. In all the cases there was marked regression and collapse of the ... -
Comparison Of Two Dosage Schedules Of Sodium Stibogluconate In The Treatment Of Visceral Leishmaniasis In Kenya
(University of NairobiDepartment of Paediatrics, 1983-01)The efficacy and safety of a single daily dose of sodium stibogluconate, 20 mg/kg body weight, given by deep intramuscular injection was compared with the conventional dose of 10 mg Sb/kg body weight in a randomised trial ... -
Effects of Tranexamic Acid on Death, Vascular Occlusive Events, and Blood Transfusion in Trauma Patients with Significant Haemorrhage (Crash-2): A Randomised, Placebo-Controlled Trial
(Department of Orthopaedic Surgery, 2006)Tranexamic acid can reduce bleeding in patients undergoing elective surgery. We assessed the effects of early administration of a short course of tranexamic acid on death, vascular occlusive events, and the receipt of blood ... -
Sickle cell disease in surgery
(Department of Orthopaedic Surgery, 2006-10-01) -
Review Article: Planning in emergencies and disasters
(Department of Orthopaedic Surgery, 2004)In surgery, emergencies are a common occurrence. Management of surgical emergencies is a component of surgical training - although this mainly comprises the clinical aspect of it. A disaster is a large-scale emergency and ... -
The management of children with Kaposi sarcoma in resource limited settings
(Department of Human Pathology, 2013-04)Kaposi sarcoma (KS) is common where HIV infection is endemic. Antiretroviral therapy (ART) has reduced the incidence in well-resourced settings but in some parts of the world access to ART is delayed. These recommendations ... -
Lymphomas in sub‐Saharan Africa–what can we learn and how can we help in improving diagnosis, managing patients and fostering translational research?
(Department of Human Pathology, 2011-06)Approximately 30 000 cases of non-Hodgkin lymphoma (NHL) occur in the equatorial belt of Africa each year. Apart from the fact that Burkitt lymphoma (BL) is very common among children and adolescents in Africa and that an ... -
Albendazole treatment of HIV-1 and helminth co-infection: A randomized, double blind, placebo-controlled trial
(Centre for Clinical Research, Kenya Medical Research Institute, KenyaCentre for Geographic Medicine Research Coast, Kenya Medical Research Institute, KenyaUniversity of Nairobi, Department of Pediatrics, Nairobi, KenyaUniversity of Nairobi, Obstetrics and Gynecology, Nairobi, KenyaDepartment of Medicine, University of Washington, Seattle, WADepartment of Biostatistics, University of Washington, Seattle, WADepartment of Epidemiology, University of Washington, Seattle, WAHuman Biology Division, Fred Hutchinson Cancer Research Center, Seattle, WACentre for Clinical Vaccinology and Tropical Medicine, University of Oxford, Headington, UK, 2008)Several co-infections have been shown to impact the progression of HIV-1 infection. We sought to determine if treatment of helminth co-infection in HIV-1 infected adults impacted markers of HIV-1 disease progression. ... -
Breast cancer diagnosis in a resource poor environment through a collaborative multidisciplinary approach: the Kenyan experience
(Department of Surgery, 2012)The majority of women with breast cancer in Kenya present with node-positive (stage II) or locally advanced Q7 disease (stage IIIB). Diagnosis is made on fine needle aspirate cytology and treatment is with surgery if ... -
Longitudinal Assessment of Human Immunodeficiency Virus Type 1 (HIV-1)-Specific Gamma Interferon Responses during the First Year of Life in HIV-1-Infected Infants
(Department of Paediatrics, University of Nairobi, Nairobi, KenyaMedicine, University of Washington, Seattle, WashingtonHuman Immunology Unit, Weatherall Institute of Molecular Medicine, Oxford University, Oxford, EnglandHuman Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, 2005)Human immunodeficiency virus type 1 (HIV-1) infection results in different patterns of viral replication in pediatric compared to adult populations. The role of early HIV-1-specific responses in viral control has not been ... -
Microstructure of the sialic acid moiety of N-glycolylneuraminyllactosylceramide and the elucidation of Hanganutziu and Deicher (HD) antigenicity
(Department of Biochemistry, 1986-03)The carboxyl (-COOH) group of heterophile Hanganutziu and Deicher (HD) antigen-active ganglioside (N-glycolylneuraminyllactosyl-ceramide) was esterified (-CO2CH3) by methyl iodide and then reduced to a primary alcohol ... -
A potential radioimmunoassay system for detection of Hanganutziu-Deicher type heterophile antigen (s) and antibodies in tissues and fluids
(Department of Biochemistry, 1985-06)A relatively simple, specific and sensitive radioimmunoassay system has been developed for the detection of heterophile Hanganutziu-Deicher (H-D) antigen(s) and antibodies. The 125I-labeled H-D antigen-active molecule used ... -
Erythroid Aplasia in Riboflavin-Deficient Baboons and its Relation to Marasmus and Kwashiorkor
(Department of Biochemistry, 1967-11)An erythroid hypoplasia characterized by falls in red cell precursors, haemoglobin, packed cell volume, reticulocytes and sometimes platelets, resembling that which occurs in marasmus and kwashiorkor, has been produced ... -
Distinct differences in a cyclin D1 single nucleotide polymorphism between ethnic groups
(Department of Clinical Medicine and Therapeutics, 2001-09)Cyclin D1, encoded by the CCND1 gene, is a key regulator of the cell cycle at the G1/S phase checkpoint. A common A/G single nucleotide polymorphism (SNP) at nt870 of the CCND1 gene has been associated with outcome in ...
