Faculty of Health Sciences (FHS): Recent submissions
Now showing items 6521-6540 of 10418
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Neuronal effects of experimentally induced hydrocephalus in newborn rats.
(Department of Surgery, University of Nairobi, 1985)To determine the effects of increased cerebrospinal fluid (CSF) pressure on neuronal morphology, obstructive hydrocephalus was induced by injecting kaolin into the fourth ventricle and cisterna magna of 1-day-old rats. The ... -
District focus management of psychiatric emergencies in general practice.
(Department of Psychiatry, University of Nairobi, 1986) -
Severe self-mutilation among Kenyan psychotics
(Department of Psychiatry, University of Nairobi, 1986)Four case reports are presented of psychotic patients seen in clinical practice in Nairobi over a period of one year, who inflicted serious bodily harm to themselves during that period. Possible psychopathological basis ... -
Neonatal haematology in Zimbabwe. I: The platelet parameters
(University of NairobiDepartment of Haematology and Blood Transfusion, 1994-04)Platelet parameters were determined in 600 full term healthy Zimbabwean neonates using a Coulter Counter Model S Plus. The mean +/- s.d. values obtained with ranges were: Platelet count 235 +/- 67 (range 100-410) x 10(9) ... -
On conflict resolution and change.
(1993) -
A randomized, double-blind, placebo-controlled study of buprenorphine was carried out in 20 patients after cholecystectomy. The drug was given on "patient demand" either i.m. (0.15 mg) or sublingually (0.2 mg) with a minimum dose interval of 30 min. Over the 24-h study period the mean demand by the sublingual route was 0.8 mg (range 0.6-1.2 mg) and by the i.m. route 0.66 mg (range 0.45-0.9 mg). Pain relief, by visual analogue scales and grading, was similar. Plasma buprenorphine concentrations varied more after sublingual administration. Either route was effective for the treatment of pain when administered by "patient demand".
(Department of Surgery, University of Nairobi, 1986)A randomized, double-blind, placebo-controlled study of buprenorphine was carried out in 20 patients after cholecystectomy. The drug was given on "patient demand" either i.m. (0.15 mg) or sublingually (0.2 mg) with a minimum ... -
TP53 mutations, human papilloma virus DNA and inflammation markers in esophageal squamous cell carcinoma from the Rift Valley, a high-incidence area in Kenya.
(University of Nairobi,Department of Biochemistry, 2011-10)BACKGROUND: Squamous Cell Carcinoma of Esophagus is one of the most common malignancies in both men and women in eastern and south-eastern Africa. In Kenya, clinical observations suggest that this cancer is frequent in ... -
The difference between effectiveness and efficacy of antimalarial drugs in Kenya
(University of NairobiCollege of Humanities Sciences, 2004)Objective:To demonstrate the difference between effectiveness and efficacy of antimalarial (AM) drugs in Kenya. Methods:We undertook a series of linked surveys in four districts of Kenya between 2001 and 2002 on (i) ... -
Health delivery standards: vested interests in health planning.
(USAID/Tanzania, Dar es Salaam., 1994)The thread of this paper is that vested interests prevail consistently in the formulation of health policy and provision of health services. Several African countries illustrate how the health care standard becomes an end ... -
The influence of nitrous oxide on oxyhaemoglobin dissociation and measurement of oxygen tension
(Department of Surgery, University of Nairobi, 1986)There are conflicting reports of the effect of nitrous oxide on the oxyhaemoglobin dissociation curve. We have therefore determined P50 of haemoglobin in the presence of either nitrous oxide or nitrogen and studied the ... -
Inhibitory effect of Trypanosoma brucei brucei on Glossina morsitans midgut trypsin in vitro
(The International Centre of Insect Physiology and Ecology, Nairobi, KenyaCollege of Health Sciences, University of Nairobi, 1992)The ability of Trypanosoma brucei brucei to inhibit trypsin or trypsin-like enzymes in crude midgut homogenates of Glossina morsitans morsitans was studied in vitro. The isolated parasites caused a concentration-dependent ... -
Mode of action of halothane on histamine-induced airway constriction in dogs with reactive airways.
(Department of Surgery, University of Nairobi, 1986)o determine if clinical concentrations of halothane have direct relaxant effects on airway smooth muscle, the authors compared dose-response curves to histamine in the control state (thiopental) and during halothane ... -
Studies on tsetse midgut factors that induce differentiation of blood-stream Trypanosoma brucei brucei in vitro
(International Centre for Insect Physiology and Ecology, Nairobi, Kenya.College of Health Sciences, University of Nairobi, 1992)An in vitro system for studying the transformation of bloodstream forms of Trypanosoma brucei brucei into procylic (midgut) forms is described. In this system, transformation of the parasites was stimulated by Glossina ... -
In vitro activities of 2,4-diaminoquinazoline and 2,4-diaminopteridine derivatives against Plasmodium falciparum
(University of NairobiSchool of Medicine, 2004)The activities of 28 6-substituted 2,4-diaminoquinazolines, 2,4-diamino-5,6,7,8-tetrahydroquinazolines, and 2,4-diaminopteridines against Plasmodium falciparum were tested. The 50% inhibitory concentrations (IC(50)s) of ... -
Aetiology of liver cirrhosis in Kenya.
(Department of Surgery, University of Nairobi, 1986)No abstract available -
Inhibition of Glossina morsitans midgut trypsin activity by D-glucosamine
(International Centre of Insect Physiology and Ecology, Nairobi, Kenya.College of Health Sciences, University of Nairobi, 1993)The effect of the amino sugar D-glucosamine on trypsin in crude midgut homogenates of Glossina morsitans morsitans was studied in vitro. The results showed that the midgut trypsin was specifically and competitively inhibited ...
