Faculty of Health Sciences (FHS): Recent submissions
Now showing items 7021-7040 of 10418
-
Helicobacter pylori eradication: A randomised comparative trial of 7-day versus 14-day triple therapy.
(Department of Medicine, Aga Khan University Hospital, Nairobi, 2012)Background. Helicobacter pylori is associated with several upper gastrointestinal conditions including chronic gastritis, peptic ulcer disease, and gastric malignancy. Proton pump inhibitor-based triple therapies are ... -
Assessment of some shock absorbing insoles
(1986)Due to the increase in prescription of insoles to relieve symptoms due to skeletal shocks at heel strike a pilot study was initiated to look at some materials used for this purpose. Five materials were examined (Plastazote, ... -
Short-term effect of zidovudine on plasma and genital human immunodeficiency virus type 1 and viral turnover in these compartments
(University of Nairobi.Department of Pediatrics, University of Nairobi, Nairobi, Kenya, 2003-07)The effect of zidovudine on plasma and genital human immunodeficiency virus type 1 (HIV-1) was determined in 42 antiretroviral-naive HIV-1-seropositive women in Nairobi. After 7 days of zidovudine treatment, HIV-1 RNA ... -
Rapid sequencing of the p53 gene with a new automated DNA sequencer
(Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada., 1998)p53 is the most commonly mutated gene in human cancers. Approximately 90% of the p53 gene mutations are localized between domains encoding exons 5 to 8. Sequencing methods currently available are tedious and time-consuming ... -
Autoantibody profile in thyroid diseases in black Kenyans
(Department of Medicine, University of Nairobi, 1984)A controlled prospective study of autoantibody profile on black Kenyan patients with non-toxic goitre (116), thyrotoxicosis (131) and age, sex matched hospital controls is reported. The prevalence of thyroid microsomal and ... -
Rapid and accurate determination of (CAG)n repeats in the androgen receptor gene using polymerase chain reaction and automated fragment analysis.
(Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada, 1999)To develop and evaluate a new method for determination of the CAG repeat length in Exon 1 of the androgen receptor gene. DESIGN AND METHODS: The method is based on PCR amplification of a DNA region encompassing the repeats ... -
Impact of genetic targets on cancer therapy in acute myelogenous leukemia.
(Department of Internal Medicine, Penn State Milton S. Hershey Medical Center, Hershey, PA 17033, USA., 2013)Acute myelogenous leukemia (AML) is characterized by uncontrolled proliferation of the cells of myeloid origin. It can present at all ages, but is more common in adults. It is one of the most common leukemias in adults and ... -
A review of iodine deficiency disorders in Kenya
(Department of Medicine, University of Nairobi, 1988)No abstract available. -
Sequence analysis of the human kallikrein gene locus identifies a unique polymorphic minisatellite element
(Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada, 2001)Minisatellites are repetitive sequences of DNA that are present throughout the genome. Although the origin and function of these minisatellites is still unknown, they found clinical applications as markers of many diseases, ... -
Quantitative analysis of kallikrein 15 gene expression in prostate tissue
(Department of Urology, University Hospital Charité, Humboldt University, Berlin, German, 2003)The newly discovered human kallikrein 15 gene KLK15 has been shown in preliminary analysis to be associated with more aggressive types of prostate cancer. We quantitatively measured and compared gene expression of KLK15 ... -
Chronic splenomegaly in Nairobi, Kenya. II. Portal hypertension.
(University of NairobiDeppartment of Medicine, 1987)Eighty-five patients with chronic splenomegaly and proven oesophageal varices were studied at Kenyatta National Hospital, Nairobi. The major defined groups were hepatosplenic schistosomiasis (24%), cirrhosis (20%) and ... -
Schistosoma mansoni in the baboon: modulation of pathology after vaccination with polyclonal anti-idiotypic antibodies.
(Parasitology, National Museums of Kenya, Nairobi, Kenya., 1995)Vaccination of five baboons with an anti-idiotypic vaccine to irradiated Schistosoma mansoni cercariae resulted in nearly 19% protection compared to 39% protection conferred to five baboons vaccinated with an irradiated ... -
Biochemical and molecular diagnosis of glutaric aciduria type 1 in a black South African male child: case report.
(University of NairobiDepartment of Chemical Pathology, 2001)Glutaric aciduria type 1 (GA-1) is an inborn error of metabolism caused by a deficiency of the mitochondrial enzyme glutaryl-Co enzyme A dehydrogenase. GA-1 is not uncommon amongst Caucasians but to the best of our knowledge, ... -
Comparison of human immunodeficiency virus type 1 viral loads in Kenyan women, men, and infants during primary and early infection
(University of Nairobi.Department of Biostatistics, University of Washington and Division of Public Health SciencesDepartment of Paediatrics and Child Health, Univeristy of Nairobi, Kenya, 2003-06)Steady-state levels of human immunodeficiency virus type 1 (HIV-1) RNA in plasma reached at approximately 4 months postinfection are highly predictive of disease progression. Several studies have investigated viral levels ... -
Suspected in utero infection in a boran heifer experimentally infected with Trypanosoma vivax.
(Veterinary Pathology, Microbiology & Parasitology, 1996) -
TDR thirty years on: taking stock and envisioning the future for the Special Programme for Research and Training in Tropical Diseases
(University of NairobiSchool of medicine,University of NairobiDepartment of Public Health Sciences, University of TorontoDepartment of Medicine, Aga Khan University HospitalInstitute of Anthropology, University of Copenhagen, Copenhagen, Denmark, 2008-11) -
Collagen Ialpha1 and vitamin D receptor gene polymorphisms in South African whites, blacks and Indians.
(University of NairobiDepartment of Chemical Pathology,, 2001-11)To determine whether polymorphic differences exist between black, white and Indian South Africans in genes associated with bone mineral density and osteoporosis. DESIGN: Genes selected were the vitamin D receptor (Apa ... -
The effect of experimental infection of Boran cattle in early and mid-pregnancy with Trypanosoma vivax.
(Kenya Trypanosomiasis Research Institute, Kikuyu, Kenya., 1996)Six susceptible Galana and five trypanotolerant Orma Boran (Bos indicus) cattle were infected experimentally with Trypanosoma vivax KETRI 2501 by cyclical transmission using Glossina morsitans during early and mid-pregnancy. ... -
The effect of age, sex and education on reception and retention of health information: lessons from a rural area of Kenya.
(Kenya Medical Research Institute, Nairobi., 1991)No abstract available
