Faculty of Health Sciences (FHS): Recent submissions

Now showing items 7141-7160 of 10418

    • Infant CD4 C868T polymorphism is associated with increased human immunodeficiency virus (HIV-1) acquisition 

      Choi, RY; Farquhar, C; Juno, J; Mbori-Ngacha, DA; Lohman-Payne, B; Vouriot, F; Wayne, S; Tuff, J; Bosire, R; John-Stewart, G; Fowke, K (University of Nairobi.Department of Paediatrics and Child Health, Univeristy of Nairobi, Kenya, 2010-06)
      The C868T single nucleotide polymorphism (SNP) in the CD4 receptor encodes an amino acid change that could alter its structure and influence human immunodeficiency virus (HIV-1) infection risk. HIV-1-infected pregnant women ...

    • Interpreting tests for iron deficiency among adults in a high HIV prevalence African setting: routine tests may lead to misdiagnosis 

      Lewis, DK; Whitty, CJ; Epino, H; Letsky, EA; Mukiibi, JM; Broek, NR (University of NairobiFaculty of medicine, 2007-06)
      We evaluated peripheral blood tests to diagnose iron deficiency on medical wards in Blantyre, Malawi, where infection and HIV are prevalent. We compared full blood count, ferritin and serum transferrin receptor (TfR) levels ...

    • Multiregional population analysis: the accounting approach 

      Rees, P. H (1979)
      The concepts and methods of demographic accounting applied to multiregional population analysis are summarized with the illustrations drawn from a recently constructed set of accounts for the East Anglia and South East ...

    • Clinical and pathological evaluation of large loop diathermy excision of the transformation zone. 

      Poka, R; Chappel, M; Lee, C L; Aggarwal, V P (School of medicine,University of NairobiDepartment of Obstetrics and Gynaecology, Southend NHS Trust Hospital Rochford, United Kingdom., 1995)
      In order to make accurate diagnosis and to carry out treatment of cervical preneoplastic disease, large loop diathermy excision of the transformation zone was performed in 98 patients. The colposcopic assessment was indicated ...

    • Association of reduction of AFB1-induced liver tumours by antioxidants with increased activity of microsomal enzymes 

      Wakhisi, J; Kilonzo, MM; Nyandieka,HS (Department of Biochemistry, Faculty of Medicine, University of Nairobi, Kenya, 1990)
      The influence of nutritional factors on aflatoxin B1 (AFB1)-induced liver tumours was investigated in rats. When a dose of 500 micrograms AFB1/kg body weight was given to rats in the absence of any anticarcinogen, 80 per ...

    • Renal clearance of pentavalent antimony (sodium stibogluconate) 

      Rees, P. H; Keating, M. I; Kager, P. A; Hockmeyer, W. T (1980)
      Kenyan kala-azar is sometimes unresponsive to a standard course of sodium stibogluconate. The renal excretion of sodium stibogluconate was therefore studied in patients with kala azar and in volunteers; both urine and serum ...

    • Artemether/lumefantrine in the treatment of uncomplicated falciparum malaria 

      Kokwaro, G; Mwai, L; Nzila, A (University of NairobiCollege of Humanities Sciences, 2007)
      At present, artemether/lumefantrine (AL) is the only fixed-dose artemisinin-based combination therapy recommended and pre-qualified by WHO for the treatment of uncomplicated malaria caused by Plasmodium falciparum. It has ...

    • Post kala-azar uveitis 

      Dechant, W; Rees, P. H; Kager, P. A; Klauss, V; Adala, HS (1980)
      Three patients who developed bilateral anterior uveitis at the end of, or soon after, the apparently successful treatment of visceral leishmaniasis are described. The uveitis gave rise to secondary glaucoma in 2 of the ...

    • Illness during pregnancy and bacterial vaginosis are associated with in-utero HIV-1 transmission 

      Farquhar, C; Mbori-Ngacha, DA; Overbaugh, J; Wamalwa, D; Harris, J; Bosire, R; John-Stewart, G (University of Nairobi.Department of Paediatrics and Child Health, Univeristy of Nairobi, Kenya, 2010-01)
      HIV-1 transmission in utero accounts for 20-30% of vertical transmission events in breast-feeding populations. In a prospective study of 463 HIV-1-infected mothers and infants, illness during pregnancy was associated with ...

    • Allopurinol in the treatment of visceral leishmaniasis 

      Kager, P. A; Rees, P. H; Wellde, B. T; Hockmeyer, W. T; Lyerly, W. H (1981)
      Allopurinol was used in the treatment of 10 patients with kala-azar. Of six patients who had previously failed to respond satisfactorily to Pentostam, "cures" were achieved in four. However, it was necessary to add Pentostam ...

    • Percutaneous retrieval of a fully expanded maldeployed left subclavian artery stent: nightmares in cath lab. 

      Aggarwal, V P; Malik, A; Gupta, S K (School of medicine,University of NairobiDepartment of Cardiology, Indraprastha Apollo Hospitals, New Delhi, India, 2009-01)
      A self expendable Nitinol stent was accidently maldeployed when precise positioning was being done in a pre dilated 100% occluded left subclavian artery. A significant part of stent was hanging into the arch of aorta ...

    • Short Course Chemotherapy For Pulmonary Tuberculosis In Routine Service In Kenya 

      Babu, Swai O .; Aluoch, J A; Githui, W; Darbyshire, J H (University of NairobiKenya Medical Research Institute, Respiratory Diseases Research Centre, Nairobi., 1990)
      The results are reported of the application of a short-course regimen for pulmonary tuberculosis in routine service in three districts in Kenya. All patients were treated in hospital for one month receiving Streptomycin, ...

    • Evidence for a branched electron transport chain in Trypanosoma brucei 

      Njogu, R M; Whittaker, C J; Hill, G C (Department of Biochemistry, University of Nairobi, 1980)
      The flow of electrons the terminal oxidases present in the bloodstream and procyclic trypomastigotes of Trypanosoma brucei LUMP 1026 has been investigated by the use of salicylhydroxamic acid (SHAM) and cyanide. Respiration ...

    • Medical Research: Are we doing enough in Africa? 

      Kokwaro, G (University of NairobiCollege of Humanities Sciences, 1998)
      As we look forward to the end of this Century and the beginning of the next, our politicians are busy telling us about their plans to turn our countries into New Industrialised Nations (NINS) by the year 2010 (or is it ...

    • Low risk of death, but substantial program attrition, in pediatric HIV treatment cohorts in Sub-Saharan Africa 

      Whitescarter, J; Miotti, P; Bazin, B; Blesson, S; Arrivé, E; Marquis, B; Tumwesigye, N; Brinkhof, MW; Fassinou, P; Cotton, M; Wemin, L; Boulle, A; Holland, M; Renner, L; Kariyo, P; Aveika, A; Azondekon, A; Carter, R; Leroy, V; Kieffer, MP; Namale, L; Newell, ML; Mbori-Ngacha, DA; et al (University of Nairobi.Department of Paediatrics and Child Health, Univeristy of Nairobi, Kenya, 2008-12)
      BACKGROUND: To date, an estimated 10% of children eligible for antiretroviral treatment (ART) receive it, and the frequency of retention in programs is unknown. We evaluated the 2-year risks of death and loss to follow-up ...

    • Ovine and Human Placental IgG inhibit Human Natural Killer Cell Cytotoxicity in vitro. 

      Omwandho, C A; Peters, C; Roberts, T K; Tinneberg, H R; Tumbo-Oeri, A G (University Of NairobiDepartment of Biochemistry, University of Nairobi, 2001)
      To determine the effect of ovine and human placental IgG on human Natural Killer (NK) cell cytotoxicity in vitro placental IgG was eluted at acidic pH and purified by ion exchange and subsequently by affinity chromatography ...

    • The effects of malaria control on nutritional status in infancy 

      Snow, RW; Molyneux, CS; Njeru, EK; Omumbo, J; Nevill, CG; Muniu, E; Marsh, K (University of Nairobi.Department of Medicine, 1997-04)
      Both malaria and undernutrition are major causes of paediatric mortality and morbidity in sub-Saharan Africa. The introduction of insecticide-treated bed nets (ITBN) during a randomized controlled trial on the Kenyan coast ...

    • Importance of controlled trials in medicine 

      Njeru, EK (University of Nairobi.College of Health Sciences, University of Nairobi, Kenya, 1996-03)

    • Isolation And Properties Of A 23 Kd Haemolymph Protein From Tsetsefly G.m Morsitan 

      Nguu, EK; Ochanda, JO; Osir, EO; Olembo, NK (University of NairobiFaculty of medicine, 1993-06)

    • Clinical and laboratory characteristics of hospitalised patients with neurological manifestations of HIV/AIDS at the Nairobi hospital 

      Jowi, JO; Mativo, PM; Musoke, SS (University of Nairobi.College of Health Sciences, University of Nairobi, Kenya, 2007-02)
      OBJECTIVE: To determine the profile of clinical and laboratory characteristics of hospitalised HIV positive patients with neurological complications at a private hospital in Nairobi, Kenya from January 2000 to June ...