Faculty of Health Sciences (FHS): Recent submissions
Now showing items 7741-7760 of 10418
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Dental Plaque And Gingival Condition Of Mentally Handicapped Children In Mathare Special Training Centre Nairobi, Kenya
(School of Dental Science,University of Nairobi, 1988-05) -
Non-typhi salmonella in children with severe malaria
(University of Nairobi.Department of Pharmaceutics & Pharmacy Practice, Faculty of Pharmacy, College of Health Sciences, 2002-12)OBJECTIVE: To determine the association between Plasmodium falciparum malaria and non-typhi Salmonella in children. DESIGN: Cross-sectional hospital based study. SETTING: Kilifi District Hospital (KDH) between ... -
A rapid staining technique for Leishmania parasites in splenic aspirate smears
(Department of Medical Microbiology, University of Nairobi, Kenya., 1989)A quick and suitable method for staining Leishmania donovani and other blood protozoa is described. The method, which could have wide applications, is a modification of Field's staining technique as used for malaria ... -
Incidence Of The Second Canal The Upper Second Premolar
(University of NairobiDepartment Of Paediatric Dentistry & Orthodontics, 1988-05) -
Population pharmacokinetics of intramuscular gentamicin administered to young infants with suspected severe sepsis in Kenya
(University of Nairobi.Department of Pharmaceutics & Pharmacy Practice, Faculty of Pharmacy, College of Health Sciences, 2003-07)AIMS: To determine the population pharmacokinetics of intramuscular (i.m.) gentamicin in African infants with suspected severe sepsis. METHODS: Samples were withdrawn 1 h after a single i.m. injection of 8 mg x kg(-1) ... -
Selective and sensitive liquid chromatographic assay of amodiaquine and desethylamodiaquine in whole blood spotted on filter paper
(University of Nairobi.Department of Pharmaceutics & Pharmacy Practice, Faculty of Pharmacy, College of Health Sciences, 2004-01)We have developed a sensitive, selective and reproducible reversed-phase HPLC method with ultraviolet detection (340 nm) for the simultaneous quantification of amodiaquine (AQ) and its major metabolite, desethylamodiaquine ... -
Presenting Chief Complaints And Clinical Characteristics Among Patients Attending The Department Of Paediatric Dentistry Clinic At The University Of Nairobi Dental Hospital
(University of NairobiDepartment Of Paediatric Dentistry & Orthodontics, 2005-12)OBJECTIVES: To evaluate the chief complaints and clinical presentation among patients attending the Department of Paediatric Dentistry clinic at the University of Nairobi Dental Hospital (UONDH). DESIGN: A retrospective ... -
Use of aspirin in preeclampsia
(University of NairobiSchool of Medicine, 1995-11)One hundred and twenty consecutive patients above 12 years of age with dyspepsia were studied from June 1993 to September 1994. They underwent upper gastrointestinal endoscopy to find the mucosal lesions which were associated ... -
Hydrogen peroxide in the regulation of erythropoietin (Epo) gene expression in hepatocellular carcinoma cells
(KMA, 1996)The present studies were designed and carried out to determine if hydrogen peroxide (H2O2) is involved in the regulation of erythropoietin (Epo) gene expression and stimulation of Epo production in the hepatocellular (Hep ... -
Salmonella enteritidis
(University of NairobiDepartment Of Biochemistry, 2010) -
Factors that determine utilization of modern contraceptives in East, Central and southern Africa
(1996)A cross-sectional study to determine modern contraceptives utilization among women aged between 15 and 19 years was performed between September and October, 1991 in 5 countries of East Central and Southern Africa. The study ... -
Enone- And Chalcone-chloroquinoline Hybrid Analogues: In Silico Guided Design, Synthesis, Antiplasmodial Activity, In Vitro Metabolism, And Mechanistic Studies
(University of NairobiSchool of Pharmacy, 2011)Analogues of the previously reported antimalarial hybrid compounds 8b and 12 were proposed with the aim of identifying compounds with improved solubility and retained antimalarial potency. In silico characterization predicted ... -
Hydatid disease: research and control in Turkana, III. Albendazole in the treatment of inoperable hydatid disease in Kenya--a report on 12 cases.
(1986)The results of treatment of 12 cases of inoperable hydatid disease in Kenya using albendazole at a dose of 10 mg/kg body-weight for eight weeks are reported. In all the cases there was marked regression and collapse of the ... -
Family planning, sexually transmitted diseases and AIDS
(1996)Integration of sexually transmitted disease (STD) and HIV/AIDS control efforts into family planning programs in sub-Saharan Africa offers the potential to reach women of childbearing age when the risk of exposure to STDs ... -
Platelet function in patients with sickle cell anaemia in Nairobi
(University of NairobiUniversity of Nairobi, 1996)From July 1990 to January 1991 we studied platelet functions in 55 indigenous Kenyan patients (23 males and 32 females) with sickle cell anaemia (SCA) in steady state (SCASS) and in 20 (11 males and 9 females) SCA patients ... -
Higher resistance to Plasmodium falciparum infection in patients with homozygous sickle cell disease in western Kenya.
(Department of Medicine, University of Nairobi, 1997)Sickle haemoglobin (HbS) is considered to be protective against malaria. Malaria is fatal in homozygous sickle cell (HbSS) disease. In a cross-sectional survey by alkaline. Hb-electrophoresis of 766 residents of Western ... -
How Can Natural Products Serve As A Viable Source Of Lead Compounds For The Development Of New/novel Anti-malarials?
(University of NairobiDepartment of Pharmacetical Chemistry, 2011)Malaria continues to be an enormous global health challenge, with millions of new infections and deaths reported annually. This is partly due to the development of resistance by the malaria parasite to the majority of ... -
Fibrinolytic activity in adult Kenyan patients with sickle cell disease
(Department of Medicine, University of Nairobi, 1998)The sickling of erythrocytes increases viscosity and reduces the rate of both local circulation and arterio-venous transit time. This causes occlusion of capillaries by "microthrombin". The occlusion is implicated in the ... -
Synthesis, Biological Evaluation And Mechanistic Studies Of Totarol Amino Alcohol Derivatives As Potential Antimalarial Agents.
(University of NairobiDepartment of Biochemistry, 2012)Herein we report on the semisynthesis and biological evaluation of b-amino alcohol derivatives of the natural product totarol and other simple aromatic systems. All beta-amino alcohol derivatives of totarol exhibited higher ...
