Now showing items 8341-8360 of 10418

    • Bactericidal Activitry Of Moxifloxacin In Patients With Pulmonary Tuberculosis 

      Gillespie, SH; Gosling, RD; Uiso, LO; Sam, NE; Bongard, E; Kanduma, Esther G; Nyindo, M; Morris, RW (University of NairobiDeaprtment of Biochemistry, 2003)
      Patients in Whom Acid-fast Bacilli Smear-positive Pulmonary Tuberculosis Was Newly Diagnosed Were Randomized To Receive 400 Mg Moxifloxacin, 300 Mg Isonaizid, Or 600 Mg Rifampin Daily For 5 Days. Sixteen-hour Overnight ...
    • The incidence and distribution of retinoblastoma in Kenya 

      Nyamori, Joseph M; Kimani, Kahaki; Njuguna, Margaret W; Dimaras, Helen (University of NairobiCollege of Health Sciences, 2012)
      To determine the incidence and distribution of retinoblastoma in Kenya we performed a retrospective study of patients seen from 1st January 2006 to 31st December 2007. Of 206 suspected cases of retinoblastoma identified, ...
    • Antimalarial activity of Ajuga remota Benth (Labiatae) and Caesalpinia volkensii Harms (Caesalpiniaceae): in vitro confirmation of ethnopharmacological use. 

      Kuria, KA; De Coster, S; Muriuki, G; Masengo, W; Kibwage, IO; Hoogmartens, J; Laekeman, GM (University of NairobiFaculty of Pharmacy, 2001-02)
      Field trips to herbalists' practices in an area about 200 miles around Nairobi (Kenya) enabled us to make a list of medicinal plant species preferentially used to treat malaria. Ajuga remota and Caesalpinia volkensii were ...
    • Formulation and Evaluation of Tenoxicam Niosomes 

      Maru, S M (University of NairobiDepartment of Pharmaceutics and Pharmacy Practice, 2005)
      This study aimed at investigating the influence of varying proportions of the surfactant span 60, cholesterol and dicetylphosphate on the morphology, particle size distribution, entrapment efficiency and in vitro drug ...
    • Maternal human immunodeficiency virus-1 infection and pregnancy outcome. 

      Temmerman, M; Chomba, E N; Ndinya-Achola, JO; Plummer, F A; Coppens, M; Piot, P (University of NairobiDepartment of Medical Microbiology, 1994-04)
      OBJECTIVE: To study the impact of maternal human immunodeficiency virus type 1 (HIV-1) infection on pregnancy outcome. METHODS: Between January 1989 and December 1991, 406 HIV-1-seropositive and 407 HIV-1-seronegative ...
    • Mass antimicrobial treatment in pregnancy. A randomized, placebo-controlled trial in a population with high rates of sexually transmitted diseases. 

      Temmerman, M; Njagi, E; Nagelkerke, N; Ndinya-Achola, JO; Meheus A, A; Plummer, F A (University of NairobiDepartment of Medical Microbiology, 1995-03)
      Sexually transmitted diseases (STDs) are highly prevalent in pregnant women in many developing countries and have been associated with poor obstetric outcomes. Case detection and treatment of STDs in women is problematic ...
    • Influence of HLA supertypes on susceptibility and resistance to human immunodeficiency virus type 1 infection. 

      Kimani, J; Oyugi, J; Njagi, Elizabeth N; Wade, J; Krausa, P; Rowland-Jones, S; Ngugi, E; Bwayo, JJ; Plummer, FA; Luscher, M A; Brunham, R C; MacDonald, K S; Fowke, K R; Dunand, V A; Nagelkerke, N J; Ball, T B; Gaur, L K (Department of Medicine, 2000-05)
      Certain human leukocyte antigens, by presenting conserved immunogenic epitopes for T cell recognition, may, in part, account for the observed differences in human immunodeficiency virus type 1 (HIV-1) susceptibility. To ...
    • HIV-1 and reproductive health in Africa 

      Temmerman, M; Chomba, E N; Piot, P (University of NairobiDepartment of Medical Microbiology, 1994-02)
      In many African countries where HIV infection is mainly heterosexually transmitted a substantial proportion of women of childbearing age are now infected with the virus. This paper will review the consequences of HIV-1 ...
    • HIV-1 and immunological changes during pregnancy: a comparison between HIV-1-seropositive and HIV-1-seronegative women in Nairobi, Kenya. 

      Piot, P; Ndinya-Achola, JO; Chomba, E N; Temmerman, M; Nagelkerke, N; Bwayo, JJ (University of NairobiDepartment of Obstetrics and Gynaecology, 1995-09-09)
      OBJECTIVE: To assess changes in the proportion of CD4 and CD8 T-lymphocyte profiles during pregnancy, at delivery and postpartum, and to determine whether HIV-1 infection affects the normal profile. DESIGN AND METHODS: A ...
    • HIV-1-specific mucosal CD8+ lymphocyte responses in the cervix of HIV-1-resistant prostitutes in Nairobi 

      Kaul, R; Plummer, F A; Kimani, J; Dong, T; Kiama, P; Rostron, T; Njagi, E; MacDonald, K S; Bwayo, JJ; McMichael, A J; Rowland-Jones, S L (Department of Medical Microbiology, 2000)
      Understanding how individuals with a high degree of HIV exposure avoid persistent infection is paramount to HIV vaccine design. Evidence suggests that mucosal immunity, particularly virus-specific CTL, could be critically ...
    • Late seroconversion in HIV-resistant Nairobi prostitutes despite pre-existing HIV-specific CD8+ responses 

      Rupert, Kaul; Rowland-Jones, Sarah L.; Kimani, Joshua; Dong, Tao; Hong-Bing, Yang; Kiama, Peter; Rostron, Timothy; Njagi, Ephantus; Bwayo, JJ; MacDonald, Kelly S; McMichael, Andrew J; Plummer, Francis A (University of NairobiDepartment of Medicine, 2001-02-01)
      Resistance to HIV infection in a small group of Kenyan sex workers is associated with CD8+-lymphocyte responses to HIV cytotoxic T-lymphocyte (CTL) epitopes. Eleven prostitutes meeting criteria for HIV resistance seroconverted ...
    • Schizophrenia 

      Owiti, Fredrick R (East African Medical Journal, 1996)
      United States International University-Africa, Nairobi, Kenya. OBJECTIVE: To investigate the prevalence and pattern of substance use among an undergraduate population in a Kenyan university. DESIGN: Cross-sectional survey, ...
    • Drug Use and Abuse 

      Owiti, Fredrick R (East African Journal of Ophthalmology, 1999)
      United States International University-Africa, Nairobi, Kenya. OBJECTIVE: To investigate the prevalence and pattern of substance use among an undergraduate population in a Kenyan university. DESIGN: Cross-sectional survey, ...
    • Orbital cold abscesses with associated pansinusitis and bone involvement 

      Nyenze, Emanuel Muindi (University of Nairobi,Department of Ophthalmology, 2012)
      Orbital involvement in tuberculosis is rare even in areas where TB is endemic.1 Orbital TB is classified into five forms; classical periostitis, orbital soft tissue tuberculoma or cold abscess with no bone destruction, ...
    • The Muranga Teleophthalmology Study: Comparison of Virtual (Teleglaucoma) with in-Person Clinical Assessment to Diagnose Glaucoma 

      Nyenze, Emanuel Muindi (Middle East Journal of Opthalmology, 2013)
      Purpose: While the effectiveness of teleophthalmology is generally accepted, its ability to diagnose glaucomatous eye disease remains relatively unknown. This study aimed to compare a web-based teleophthalmology assessment ...
    • Review of treatment of epilepsy The Nairobi Journal of Medicine 

      Mbuya, S Ochanda (The Nairobi Journal of Medicine, 2005)
      OBJECTIVE: To summarise and discuss the role of neuro-electrophysiological diagnostic tests in clinical medicine. DATA SOURCES: Published original research and reviews to date. STUDY SELECTION: The review was with emphasis ...
    • Peripheral arterial disease in rheumatoid arthritis patients at the Kenyatta National Hospital, Kenya 

      Maritim, Marybeth Cherono (East African Medical Journal, 2012)
      Objective: To determine the magnitude of the rosclerotic arterial disease in Rheumatoid Arthritis(RA) patients at Kenyatta National Hospital. Design: hospital based cross-sectional study. Setting: Kenyatta National ...
    • Impact of user fees in health 

      Ayah, Richard; Ngugi, Elizabeth N (East Africa Medical Journal, 1997-12)
      OBJECTIVE: To determine the local aetiological spectrum of surgically relevant causes of abdominal pain. DESIGN: A prospective descriptive study was carried out. SETTING: Kenyatta National Hospital, Nairobi, Kenya during ...
    • Editorial on 

      Din, Mujahid Feroze (University of Nairobi,School of Medicine, 2005)
      OBJECTIVES: To estimate the prevalence of active trachoma (TF) in children aged one to nine years and potentially blinding trachoma (TT) in adults aged 15 years and older in six known trachoma-endemic districts in Kenya. ...
    • Osgood Schlatter disease: An Audit Profile of 35 Adolescents 

      Kireti, V; Atinga, J. E (University of Nairobi,, 2010)
      Background Osgood-Schlatter disease is a common cause of anterior knee pain in the adolescent. Treatment is usually conservative with surgery reserved for those who do not respond to this treatment. There is little published ...