Faculty of Health Sciences (FHS): Recent submissions
Now showing items 8781-8800 of 10418
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Minor Flavanones from Erythrina abyssinica
(Department of Botany, University of NairobiDepartment of Medicine, University of Nairobi,Department of Natural Medicinal Chemistry, Kobe Pharmaceutical University, Motoyamakita-machi, Higashinada-ku, Kobe 658, Japan, 1998)Four new prenylated flavanones, abyssinone-V 4'-methyl ether (1) and abyssinoflavanones IV (2), V (3), and VI (4), have been isolated as minor flavanones from the African medicinal plant, Erythrina abyssinica, together ... -
Cytotoxic C-benzylated dihydrochalcones from Uvaria acuminata
(2004)Two new C-benzylated dihydrochalcones, isochamuvaritin (1) and acumitin (2), have been isolated from the African medicinal plant Uvaria acuminata, together with the previously reported benzylbenzoate (3), uvaretin (4), ... -
Chloroquine Drug Interactions Part I: Interaction with drugs acting at the neuromuscular junction
(1998)Chloroquine is extensively used in the management of malaria in Kenya. It is widely available for self medication. Often it is used concurrently with other drugs. In the present paper, possible drug interactions with ... -
A comparison of organochlorine pesticide residues in maternal adipose tissue, maternal blood, cord blood, and human milk from mother/infant pairs
(Department of Public Health, Pharmacology and Toxicology, College of Agriculture and Veterinary Sciences, University of Nairobi, Kenya, 1992)A total of 41 samples of maternal blood, milk, subcutaneous fat and umbilical cord blood were collected from mothers giving birth by Caesarean operation at Kenyatta National Hospital in Nairobi in 1986. The samples were ... -
Essential oil contents and chemical varieties in Kenya
(1981)The distribution of cathinone and d-norpseudoephedrine in Catha edit/is plants from 2 different geographical localities has been investigated. There was no difference in the chemical constituents of Catha material from 2 ... -
Pharmacogenetics of drug metabolizing enzymes in the luo, kikuyu and maasai ethinic populations of Kenya
(1981)There is great heterogeneity in the way individuals and populations respond to medications in terms of both host toxicity and efficacy. It is now well recognized that genetic differences in drug metabolism and disposition ... -
Incidence of Carabelli's trait in Kenyan Africans and Asians
(Department of Human Anatomy, University of Nairobi, 1982)Examination for incidence of Carabelli's trait was done on 1267 Africans and 781 Asian school children, 298 dental plaster casts and 248 skulls of Africans. The African sample is composed of 80% Bantu, 20% Nilote, and ... -
Evaluation of the potential of the marine sponges of the Zanzibar Island to yield antimalarial and antimicrobial active compounds
(2010)Emergence of new and re-emergence of old infections continue to elude prospects of reducing morbidity and mortality caused by microbial infections. Trends of resistance to currently in use antimicrobials and antimalarials ... -
Palatal analysis and osteology of the hard palate of the Kenyan African skulls.
(Department of Human Anatomy, University of Nairobi, 1984)One hundred twenty-five dry skulls from Kenya that consisted of about 90% Bantu individuals were examined to obtain data on the gross anatomy of the hard palate. The palatine index showed that 43.2% of the total sample of ... -
Bacteriology of acute septic arthritis
(Department of paediatrics, University of Nairobi, 1991-08)In a study of septic arthritis infants formed the bulk of patients though, notably, neonates were not encountered. Gram-negative bacterial of the Salmonella species, especially Salmonella typhimurium and Klebsiella species ... -
Metabolism of cathinone to d-norpseudoephedrine in humans.
(1983)Cathinone, a potent psychostimulant isolated from young shoots of Catha edulis was given to four human volunteers. Examination of urine collected from the volunteers at predetermined intervals showed the presence of unchanged ... -
A competitive enzyme-linked immunosorbent assay for determination of chloramphenicol.
(2007)Chloramphenicol is a broad-spectrum antibiotic shown to have specific activity against a wide variety of organisms that are causative agents of several disease conditions in domestic animals. Chloramphenicol has been banned ... -
Sexual abuse of children as seen at Kenyatta National Hospital.
(Department of paediatrics, University of Nairobi, 1992-07)A retrospective study of 21 sexually abused children admitted to the Kenyatta National Hospital, Nairobi, Kenya, between January 1984 and December 1985 is presented. The peak incidence of sexual abuse was in the age group ... -
Antimalarial activity of some plants traditionally used in treatment of malaria in Kwale district of Kenya.
(2007)Methanolic and water extracts of five medicinal plant species used for treatment of malaria in traditional/cultural health systems of Kwale people in Kenya were tested for antimalarial activity against Plasmodium falciparum ... -
Patterns of nerve regeneration in dental pulps of monkeys following surgical transection at 1 year.
(Department of Human Anatomy, University of Nairobi, KenyaDepartment of Orthodontics, University of North Carolina, School of Dentistry, Chapel Hill, 1993)Previous studies have reported revascularization and reorganization of dental pulp chambers with periodontal tissues of monkeys following complete surgical transection through a portion of the apical roots. This study ... -
The in vitro anti-plasmodial and in vivo anti-malarial efficacy of combinations of some medicinal plants used traditionally for treatment of malaria by the Meru community in Kenya.
(2008)The use of herbal drugs as combinations has existed for centuries in several cultural systems. However, the safety and efficacy of such combinations have not been validated. In this study, the toxicity, anti-plasmodial and ... -
Human immunodeficiency virus type 1-infected cells in breast milk: association with immunosuppression and vitamin A deficiency
(Department of paediatrics, University of Nairobi, 1995-12)Breast milk samples from human immunodeficiency virus type 1 (HIV-1)-seropositive women were analyzed by polymerase chain reaction to determine the prevalence and determinants of HIV-1-infected cells in breast milk. Breast ... -
Quaternary isoquinoline alkaloids from Xylopia parviflora.
(2004)From the quaternary alkaloidal fraction of the bark and the root of Xylopia parviflora (Annonaceae), four isoquinoline alkaloids, xylopinidine, dehydrocoreximine, N, N-dimethylanomurine and N-methylphoebine were isolated ... -
Antinociceptive effects of the extracts of Xylopia parviflora bark and its alkaloidal components in experimental animals.
(2010)In the present study, we attempted to elucidate the antinociceptive activity of Xylopia parviflora bark using the acetic acid-induced writhing test, hot plate test, and formalin test in mice. The MeOH extract (100 and 200 ... -
Hydroxyespintanol and schefflerichalcone: two new compounds from Uvaria scheffleri.
(2010)A chemical investigation of the petroleum ether extract and chloroform extract of the root of Uvaria scheffleri Diels (Annonaceae) led to the isolation of two new compounds, named hydroxyespintanol (1) and schefflerichalcone ...
