Case report of Xeroderma pigmentosum associated with multiple skin cancers and strong family history.

Abstract

Xeroderma pigmentosum (XP) is a condition inherited as an autosomal recessive trait and is characterized by photosensitivity, pigmentary changes, premature skin ageing and malignant tumour development resulting from a defect in DNA repair. A case of stage 3 Xeroderma pigmentosum affecting a young girl and her siblings is presented. This is a rare medical condition which may cause difficulties in making a timely diagnosis.