Clinical presentation of patients with adult onset still’s disease in Nairobi: case series

Abstract

Introduction: Adult Still’s Disease (ASD) is a systemic inflammatory disorder of unknown etiology, typically characterized by a clinical triad (daily spiking high fevers, evanescent rash, arthritis), and a biological triad (hyperferritinemia, hyperleukocytosis with neutrophilia and abnormal liver function test). Objective: This case series set out to describe the clinical characteristics of patients with ASD seen at a rheumatology clinic in Nairobi. Results: After a record search, 8 patients were noted to have ASD. Fever and arthritis were noted to be most predominant presenting features with almost all the patients having hyperferritinemia.