AF-2 Induced Chromosome Aberrations in Vicia faba Root Meristematic Cells
Abstract
The antimicrobial food additive AF-2 is mutagenic in bacteria, Neurospora, yeast and Drosophila. AF-2 breaks mammalian chromsomes. We studied by Feulgen staining the types and distribution of chromosome aberrations induced by AF-2 in Vicia faba root meristems. AF-2 induces (a) mitostasis resulting in accumulation of cells in G1, S or G2 phase, (b) chromosome condensation, (c) pycnosis of the interphase nuclei and (d) anaphase bridges and micronuclei. The bridges involve all the six chromosome pairs but largely the SAT-chromosomes. Attachments are confined to secondary constrictions and chromosome tips. These effects are likely to be due to an indirect action of AF-2 on the genetic material.
URI
https://www.jstage.jst.go.jp/article/cytologia1929/49/1/49_1_209/_articlehttp://hdl.handle.net/11295/89526
Citation
CYTOLOGIA Vol. 49 (1984) No. 1 P 209-214Publisher
University of Nairobi